Rezulin and Rythmol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rezulin (troglitazone) and Rythmol (propafenone hydrochloride). Common drug interactions include cardiac disorder among females and chest pain among males.
The phase IV clinical study analyzes what interactions people have when they take Rezulin and Rythmol. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Rezulin?
Rezulin has active ingredients of troglitazone. eHealthMe is studying from 8,764 Rezulin users. Check the latest studies of Rezulin.
What is Rythmol?
Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.
11 people who take Rezulin and Rythmol together, and have interactions are studied.

What are the common drug interactions of Rezulin and Rythmol, by gender? *:
female:
- Cardiac disorder
- Drug ineffective
- Blood glucose increased
- Heart disease
- Hyperglycaemia (high blood sugar)
male:
- Chest pain
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Weight increased
- Abdominal pain
- Anxiety
- Ascites (accumulation of fluid in the abdominal cavity)
- Atrioventricular block (heart block)
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
What are the common drug interactions of Rezulin and Rythmol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Chest pain
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
- Weight increased
- Abdominal pain
- Anxiety
- Ascites (accumulation of fluid in the abdominal cavity)
- Atrioventricular block (heart block)
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
What are the existing conditions these people have? *
- Type 2 Diabetes: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Rezulin and Rythmol?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rezulin and Rythmol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rezulin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rythmol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rezulin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rythmol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
- Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on troglitazone and propafenone hydrochloride (the active ingredients of Rezulin and Rythmol, respectively), and Rezulin and Rythmol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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