Riboflavin and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Riboflavin (riboflavin (vitamin b2)) and Acyclovir (acyclovir). Common drug interactions include headache among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Riboflavin and Acyclovir. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Riboflavin?

Riboflavin has active ingredients of riboflavin (vitamin b2). It is often used in migraine. eHealthMe is studying from 2,869 Riboflavin users. Check the latest studies of Riboflavin.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.



On Jul, 17, 2026

25 people who take Riboflavin and Acyclovir together, and have interactions are studied.

Riboflavin and Acyclovir drug interactions.

What are the common drug interactions of Riboflavin and Acyclovir, by gender? *:

female:

  1. Headache (pain in head)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Blood potassium decreased
  4. Chronic fatigue syndrome (disorder that causes extreme fatigue)
  5. Dehydration (dryness resulting from the removal of water)
  6. Disability
  7. Drug ineffective
  8. Fall
  9. Fatigue (feeling of tiredness)
  10. Fibromyalgia (a long-term condition which causes pain all over the body)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Dyspnoea exertional (breathlessness or shortness of breath)
  3. Nasal obstruction (blockage of nose)
  4. Nasal turbinate hypertrophy (nasal turbinates become enlarged)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  7. Rhinitis allergic (inflammation of the nasal airways due to allergy)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Troponin i increased

What are the common drug interactions of Riboflavin and Acyclovir, by age (0-1 to 60+)? *:

0-1:

  1. Anaemia (lack of blood)
  2. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Chronic fatigue syndrome (disorder that causes extreme fatigue)
  3. Dehydration (dryness resulting from the removal of water)
  4. Disability
  5. Drug ineffective
  6. Fall
  7. Fatigue (feeling of tiredness)
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. Hallucination (an experience involving the perception of something not present)
  10. Headache (pain in head)

40-49:

  1. Pneumonia
  2. Rhinitis allergic (inflammation of the nasal airways due to allergy)
  3. Accident
  4. Asthma
  5. Blood pressure increased
  6. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  7. Central pain syndrome (neurological condition caused by damage or malfunction in the central nervous system)
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
  10. Craniocerebral injury (injury to cranium and brain)

50-59:

  1. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  2. Pyrexia (fever)
  3. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  4. Catheter site haemorrhage (bleeding at catheter site)
  5. Chronic kidney disease
  6. Erythema (redness of the skin)
  7. Hypersensitivity
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  9. Pneumonitis (inflammation of the walls of the alveoli in the lungs)

60+:

  1. Hepatitis (inflammation of the liver)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Syncope (loss of consciousness with an inability to maintain postural tone)
  4. White blood cell count decreased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 32.00%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 32.00%
  3. Drowsiness: 7 people, 28.00%
  4. Multiple Myeloma (cancer of the plasma cells): 6 people, 24.00%
  5. Pain: 3 people, 12.00%
  6. Insomnia (sleeplessness): 3 people, 12.00%
  7. Thrombotic Thrombocytopenic Purpura (a rare blood disorder characterized by clotting in small blood vessels of the body): 2 people, 8.00%
  8. Nausea (feeling of having an urge to vomit): 2 people, 8.00%
  9. Hiv Infection: 2 people, 8.00%
  10. Headache (pain in head): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Riboflavin and Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Riboflavin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Riboflavin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (vitamin b2) and acyclovir (the active ingredients of Riboflavin and Acyclovir, respectively), and Riboflavin and Acyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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