Rifabutin and Meropenem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rifabutin (rifabutin) and Meropenem (meropenem). Common drug interactions include cataract among females and neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Rifabutin and Meropenem. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.
What is Rifabutin?
Rifabutin has active ingredients of rifabutin. eHealthMe is studying from 2,437 Rifabutin users. Check the latest studies of Rifabutin.
What is Meropenem?
Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.
52 people who take Rifabutin and Meropenem together, and have interactions are studied.

What are the common drug interactions of Rifabutin and Meropenem, by gender? *:
female:
- Cataract (clouding of the lens inside the eye)
- Deposit eye (yellow or white deposits in eyes)
- Mycobacterial infection
- Pathogen resistance
- Retinal disorder (disease of retina)
- Fatigue (feeling of tiredness)
- Leukocytosis (increased white blood cells)
- Pyrexia (fever)
- Corneal pigmentation (colour of cornea)
- Device expulsion
male:
- Neutropenia (an abnormally low number of neutrophils)
- Electrocardiogram qt prolonged
- Drug resistance (reduction in effectiveness of a drug)
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
- Hyperkalaemia (damage to or disease of the kidney)
- Hypokalaemia (low potassium)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
- Arthralgia (joint pain)
What are the common drug interactions of Rifabutin and Meropenem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Electrocardiogram qt prolonged
- Renal failure acute (rapid kidney dysfunction)
- Drug level below therapeutic
- Immunosuppressant drug level decreased
- Diarrhoea
20-29:
- Drug resistance (reduction in effectiveness of a drug)
- Electrocardiogram t wave inversion
30-39:
- Electrocardiogram qt prolonged
- Pathogen resistance
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Mycobacterial infection
- Nausea (feeling of having an urge to vomit)
- Drug resistance (reduction in effectiveness of a drug)
- Fatigue (feeling of tiredness)
- Leukocytosis (increased white blood cells)
- Nephropathy toxic (damage to kidney due to toxins)
40-49:
- Cataract (clouding of the lens inside the eye)
- Deposit eye (yellow or white deposits in eyes)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Decreased appetite
- Depression
- Granulocytopenia (lack of granulocyte)
- Hypokalaemia (low potassium)
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
- Neutropenia (an abnormally low number of neutrophils)
- Pneumonia
50-59:
- Asthenia (weakness)
- Delirium (wild excitement)
- Diarrhoea
- Dizziness
- Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
- Hyperkalaemia (damage to or disease of the kidney)
- Neutropenia (an abnormally low number of neutrophils)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
- Dysphagia (a condition in which swallowing is difficult or painful)
60+:
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Multi-organ failure (multisystem organ failure)
- Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
- Kaposi's sarcoma aids related (a tumour caused by human herpes virus associated with aids)
- Malaise (a feeling of general discomfort or uneasiness)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it)
- White blood cell count decreased
- Hypersensitivity
- Hypoxia (low oxygen in tissues)
What are the existing conditions these people have? *
- Hiv Infection: 15 people, 28.85%
- Mycobacterium Avium Complex Infection: 12 people, 23.08%
- Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 11 people, 21.15%
- Pneumonia: 9 people, 17.31%
- Pulmonary Tuberculosis (lungs tuberculosis): 7 people, 13.46%
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 5 people, 9.62%
- Pneumocystis Jiroveci Pneumonia (fungal infection of the lungs): 5 people, 9.62%
- Diabetes: 5 people, 9.62%
- Cytomegalovirus Oesophagitis (oesophagus infection with cytomegalo virus): 5 people, 9.62%
- Candidiasis (candidiasis or thrush is a fungal infection): 5 people, 9.62%
* Approximation only. Some reports may have incomplete information.
Do you take Rifabutin and Meropenem?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rifabutin and Meropenem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rifabutin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Meropenem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rifabutin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Meropenem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on rifabutin and meropenem (the active ingredients of Rifabutin and Meropenem, respectively), and Rifabutin and Meropenem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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