Rifampin and Clotrimazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rifampin (rifampin) and Clotrimazole (clotrimazole). Common drug interactions include hepatitis toxic among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Rifampin and Clotrimazole. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Rifampin?

Rifampin has active ingredients of rifampin. It is often used in tuberculosis. eHealthMe is studying from 12,339 Rifampin users. Check the latest studies of Rifampin.

What is Clotrimazole?

Clotrimazole has active ingredients of clotrimazole. It is often used in thrush. eHealthMe is studying from 13,947 Clotrimazole users. Check the latest studies of Clotrimazole.

On Jul, 26, 2026

38 people who take Rifampin and Clotrimazole together, and have interactions are studied.

Rifampin and Clotrimazole drug interactions.

What are the common drug interactions of Rifampin and Clotrimazole, by gender? *:

female:

Hepatitis toxic
Hospitalisation
Inflammation
Neutropenia (an abnormally low number of neutrophils)
Psychological trauma
Swelling face
Swollen tongue (swelling of tongue)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Urticaria (rash of round, red welts on the skin that itch intensely)
Asthenia (weakness)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Sweating increased (excess sweating)
Thrombocytopenia (decrease of platelets in blood)
Hepatic enzyme increased
Neutropenia (an abnormally low number of neutrophils)
Anaemia (lack of blood)
Anal fissure
Blood creatinine increased

What are the common drug interactions of Rifampin and Clotrimazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)

30-39:

Anaemia (lack of blood)
Anal fissure
Burkitt's lymphoma (cancer of the lymphatic system)
Dyspepsia (indigestion)
Epistaxis (bleed from the nose)
Flushing (the warm, red condition of human skin)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Headache (pain in head)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Infectious mononucleosis (infection usually caused by the epstein-barr virus)

40-49:

Blood creatinine increased
Hidradenitis (chronic disease of a type of sweat gland)
Hyperkalaemia (damage to or disease of the kidney)
Rash pustular (redness with pustules)
Skin discolouration (change of skin colour)
Vulval abscess
Wound
Chronic kidney disease
Drug hypersensitivity
Drug ineffective

50-59:

Emotional distress
Pain
Renal failure (kidney dysfunction)
Tooth fracture
Tooth loss
Granuloma annulare (reddish bumps on the skin arranged in a circle or ring)
Hepatic enzyme increased
Neutropenia (an abnormally low number of neutrophils)
Alopecia (absence of hair from areas of the body)
Hypervolaemia (abnormally increased volume of blood)

60+:

Upper respiratory tract infection
Drug ineffective
Renal failure acute (rapid kidney dysfunction)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Urticaria (rash of round, red welts on the skin that itch intensely)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 7 people, 18.42%
Hiv Infection: 7 people, 18.42%
Osteoporosis (bones weak and more likely to break): 6 people, 15.79%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 10.53%
Granuloma Annulare (reddish bumps on the skin arranged in a circle or ring): 3 people, 7.89%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 5.26%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.26%
Nausea (feeling of having an urge to vomit): 2 people, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.26%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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