Rinvoq and Budesonide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rinvoq (upadacitinib) and Budesonide (budesonide). Common drug interactions include swollen tongue among females and colitis ulcerative among males.

The phase IV clinical study analyzes what interactions people have when they take Rinvoq and Budesonide. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Rinvoq?

Rinvoq has active ingredients of upadacitinib. eHealthMe is studying from 47,375 Rinvoq users. Check the latest studies of Rinvoq.

What is Budesonide?

Budesonide has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 42,933 Budesonide users. Check the latest studies of Budesonide.



On Aug, 12, 2026

73 people who take Rinvoq and Budesonide together, and have interactions are studied.

Rinvoq and Budesonide drug interactions.

What are the common drug interactions of Rinvoq and Budesonide, by gender? *:

female:

  1. Swollen tongue (swelling of tongue)
  2. Adenoma benign (non-cancerous tumour -secreting)
  3. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  4. Epistaxis (bleed from the nose)
  5. Gastritis (inflammation of stomach)
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Stomatitis (inflammation of mucous membrane of mouth)
  8. Abscess (pus)
  9. Bladder hypertrophy (bladder overgrowth- increase in cell size)
  10. Bladder neoplasm (bladder tumour)

male:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Drug ineffective
  3. Diarrhoea
  4. Melaena (the passage of black, tarry stools)
  5. Prostate cancer
  6. Pyrexia (fever)
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Fluid retention (an abnormal accumulation of fluid in the blood)
  9. Herpes zoster
  10. Irritability

What are the common drug interactions of Rinvoq and Budesonide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hypersensitivity
  2. Pruritus (severe itching of the skin)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Skin fissures (a crack in the skin)
  5. Skin injury

20-29:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Abdominal pain
  3. Drug ineffective
  4. Haematochezia (passage of stools containing blood)
  5. Melaena (the passage of black, tarry stools)
  6. Pyrexia (fever)
  7. C-reactive protein increased
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Feeling hot
  10. Gastrointestinal disorder (functional problems of gastrointestinal tract)

30-39:

  1. Pain in extremity
  2. Rhinalgia (pain in the nose)
  3. Abdominal distension
  4. Cytomegalovirus gastrointestinal infection (virus infection of stomach and intestine)
  5. Cytomegalovirus infection
  6. Diarrhoea
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Haematochezia (passage of stools containing blood)
  9. Infection susceptibility increased
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

40-49:

  1. Headache (pain in head)
  2. Cough
  3. Ear congestion
  4. Ear discomfort
  5. Ear infection
  6. Ear pain
  7. Erythema (redness of the skin)
  8. Hypoacusis (loss of hearing)
  9. Sunburn
  10. Arachnoid cyst

50-59:

  1. Drug ineffective
  2. Dyslipidaemia (abnormal amount of lipids)
  3. Haematoma (collection of blood outside the blood vessels)
  4. Interstitial lung disease
  5. Periorbital haemorrhage (bleeding around the eyes)
  6. Impaired healing
  7. Incision site complication
  8. Wound complication
  9. Alanine aminotransferase increased
  10. Aspartate aminotransferase increased

60+:

  1. Blood cholesterol increased
  2. Hepatic enzyme increased
  3. Herpes zoster
  4. Hypertension (high blood pressure)
  5. Nausea (feeling of having an urge to vomit)
  6. Oropharyngeal pain
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Polyuria (production of too much dilute urine)
  9. Rash
  10. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 27 people, 36.99%
  2. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 23 people, 31.51%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 16.44%
  4. High Blood Pressure: 6 people, 8.22%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

Do you take Rinvoq and Budesonide?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rinvoq and Budesonide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rinvoq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Budesonide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rinvoq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Budesonide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on upadacitinib and budesonide (the active ingredients of Rinvoq and Budesonide, respectively), and Rinvoq and Budesonide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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