Rinvoq and Chlorthalidone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rinvoq (upadacitinib) and Chlorthalidone (chlorthalidone). Common drug interactions include hypoaesthesia among females and panic attack among males.

The phase IV clinical study analyzes what interactions people have when they take Rinvoq and Chlorthalidone. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Rinvoq?

Rinvoq has active ingredients of upadacitinib. eHealthMe is studying from 47,375 Rinvoq users. Check the latest studies of Rinvoq.

What is Chlorthalidone?

Chlorthalidone has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 12,482 Chlorthalidone users. Check the latest studies of Chlorthalidone.

On Jul, 21, 2026

38 people who take Rinvoq and Chlorthalidone together, and have interactions are studied.

Rinvoq and Chlorthalidone drug interactions.

What are the common drug interactions of Rinvoq and Chlorthalidone, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Pain in extremity
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Influenza
Insomnia (sleeplessness)
Pain
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Ligament sprain (ligament stretched)

male:

Panic attack
Unresponsive to stimuli
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Dislocation of vertebra
Intervertebral disc degeneration (spinal disc degeneration)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Large intestine perforation (hole in large intestine)
Loss of consciousness
Road traffic accident

What are the common drug interactions of Rinvoq and Chlorthalidone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Panic attack
Unresponsive to stimuli
Loss of consciousness
Road traffic accident
Dehydration (dryness resulting from the removal of water)
Dizziness

40-49:

Pneumonia
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Large intestine perforation (hole in large intestine)
Nausea (feeling of having an urge to vomit)
Oral herpes (viral infection of mouth)

50-59:

Pain
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

60+:

Pain in extremity
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back pain
Blindness
Hypokalaemia (low potassium)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Sepsis (a severe blood infection that can lead to organ failure and death)
Spinal fusion surgery
Fall
Asthma

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 34 people, 89.47%
High Blood Cholesterol: 18 people, 47.37%
Diabetes: 7 people, 18.42%
Depression: 6 people, 15.79%
Pain: 5 people, 13.16%
Cardiac Disorder: 5 people, 13.16%
Hypersensitivity: 4 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.53%
Stress And Anxiety: 4 people, 10.53%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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