Risperdal and Armodafinil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperdal (risperidone) and Armodafinil (armodafinil). Common drug interactions include pain in extremity among females and altered state of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Risperdal and Armodafinil. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

What is Armodafinil?

Armodafinil has active ingredients of armodafinil. It is often used in narcolepsy. eHealthMe is studying from 4,136 Armodafinil users. Check the latest studies of Armodafinil.



On Jul, 05, 2026

18 people who take Risperdal and Armodafinil together, and have interactions are studied.

Risperdal and Armodafinil drug interactions.

What are the common drug interactions of Risperdal and Armodafinil, by gender? *:

female:

  1. Pain in extremity
  2. Foot fracture
  3. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Osteoporosis (bones weak and more likely to break)
  6. Pain
  7. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  8. Acne (skin problems that cause pimples)
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Oral herpes (viral infection of mouth)

male:

  1. Altered state of consciousness (altered state of mind)
  2. Aspergillosis oral
  3. Depression
  4. Arthralgia (joint pain)
  5. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  6. Blood bilirubin increased
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Hunger
  9. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Risperdal and Armodafinil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Arthralgia (joint pain)
  2. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Hunger

20-29:

n/a

30-39:

  1. Anxiety
  2. Dyskinesia (abnormality or impairment of voluntary movement)
  3. Fatigue (feeling of tiredness)
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Impaired work ability
  6. Ingrowing nail
  7. Insomnia (sleeplessness)
  8. Muscular weakness (muscle weakness)
  9. Pain in extremity
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

40-49:

n/a

50-59:

  1. Osteopenia (a condition where bone mineral density is lower than normal)
  2. Osteoporosis (bones weak and more likely to break)
  3. Pain
  4. Pain in extremity
  5. Altered state of consciousness (altered state of mind)
  6. Aspergillosis oral
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Herpes zoster
  9. Ileus (a painful obstruction of the ileum or other part of the intestine)
  10. Platelet count decreased

60+:

  1. Blood bilirubin increased
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Cough
  5. Dyspnoea (difficult or laboured respiration)
  6. Hospitalisation
  7. Pneumonia
  8. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 22.22%
  2. Headache (pain in head): 4 people, 22.22%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 16.67%
  4. Drowsiness: 3 people, 16.67%
  5. Tension Headache: 2 people, 11.11%
  6. Pain: 2 people, 11.11%
  7. Urination - Excessive Volume: 1 person, 5.56%
  8. Hypoaesthesia (reduced sense of touch or sensation): 1 person, 5.56%
  9. Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 1 person, 5.56%
  10. Cardiac Failure: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Risperdal and Armodafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Risperdal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Armodafinil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperdal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Armodafinil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risperidone and armodafinil (the active ingredients of Risperdal and Armodafinil, respectively), and Risperdal and Armodafinil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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