Risperdal and Bextra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperdal (risperidone) and Bextra (valdecoxib). Common drug interactions include type 2 diabetes mellitus among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Risperdal and Bextra. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

On Jul, 12, 2026

61 people who take Risperdal and Bextra together, and have interactions are studied.

What are the common drug interactions of Risperdal and Bextra, by gender? *:

female:

Type 2 diabetes mellitus
Blood triglycerides increased
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Depression
Hypertension (high blood pressure)
Chest pain
Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Neck pain

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Anxiety
Depression
Fall
Neck pain
Vision blurred
Blood pressure increased
Dizziness
Memory impairment
Abdominal pain upper

What are the common drug interactions of Risperdal and Bextra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Anxiety
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Self-injurious ideation

10-19:

n/a

20-29:

Arthralgia (joint pain)
Cellulitis (infection under the skin)
Cold sweat
Dizziness
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hypoaesthesia (reduced sense of touch or sensation)
Ingrowing nail
Mitral valve incompetence (inefficient heart valve)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Rash

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Memory impairment
Depression
Renal disorder (kidney disease)
Insomnia (sleeplessness)
Type 2 diabetes mellitus
Abdominal pain upper
Back disorder
Blood cholesterol increased
Blood pressure decreased

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Anxiety
Back pain
Blood triglycerides increased
Eye swelling
Oedema peripheral (superficial swelling)
Asthenia (weakness)
Chest pain
Depression
Diarrhoea

50-59:

Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
Pleural fibrosis (formation of fibrous tissue in lung)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pulmonary air leakage
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pyrexia (fever)
Rash

60+:

Arthralgia (joint pain)
Back pain
Viral labyrinthitis (viral inflammation of the inner ear)
Cardiovascular disorder (heart diseases)
Cerebrovascular disorder (disease of brain)
Deafness
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Depression: 20 people, 32.79%
Stress And Anxiety: 9 people, 14.75%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 9.84%
Sleep Disorder: 5 people, 8.20%
Rashes (redness): 5 people, 8.20%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 8.20%

* Approximation only. Some reports may have incomplete information.

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