Risperdal and Hydrocodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperdal (risperidone) and Hydrocodone (hydrocodone bitartrate; ibuprofen). Common drug interactions include chronic kidney disease among females and anaphylactic reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Risperdal and Hydrocodone. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

On Jul, 11, 2026

20 people who take Risperdal and Hydrocodone together, and have interactions are studied.

Risperdal and Hydrocodone drug interactions.

What are the common drug interactions of Risperdal and Hydrocodone, by gender? *:

female:

Chronic kidney disease
Suicidal ideation
Anxiety disorder
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Lung disorder (lung disease)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Pathological gambling
Retinal dystrophy (progressive weakness and wasting of the retina)
Anxiety

male:

Anaphylactic reaction (serious allergic reaction)
Hyperglycaemia (high blood sugar)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nausea (feeling of having an urge to vomit)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pancreatitis (inflammation of pancreas)

What are the common drug interactions of Risperdal and Hydrocodone, by age (0-1 to 60+)? *:

0-1:

Blood glucose increased
Blood potassium decreased
Delirium (wild excitement)
Dementia (madness)
Diabetic hyperosmolar coma (diabetes coma due to extremely high blood sugar (glucose) levels; extreme lack of water (dehydration))
Electrolyte imbalance
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

2-9:

n/a

10-19:

n/a

20-29:

Anaphylactic reaction (serious allergic reaction)

30-39:

Completed suicide (act of taking one's own life)
Suicide attempt
Retinal dystrophy (progressive weakness and wasting of the retina)

40-49:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hyperglycaemia (high blood sugar)
Type 2 diabetes mellitus

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Surgery

60+:

Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the existing conditions these people have? *

Pain: 9 people, 45.00%
Depression: 8 people, 40.00%
Hypersensitivity: 7 people, 35.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 30.00%
High Blood Cholesterol: 5 people, 25.00%
Oedema (fluid collection in tissue): 4 people, 20.00%
Multiple Allergies (allergy to multiple agents): 4 people, 20.00%
Asthma: 4 people, 20.00%
Irritable Bowel Syndrome: 3 people, 15.00%
Headache (pain in head): 3 people, 15.00%

* Approximation only. Some reports may have incomplete information.

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