Risperdal and Zovirax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperdal (risperidone) and Zovirax (acyclovir sodium). Common drug interactions include pleural effusion among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Risperdal and Zovirax. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

What is Zovirax?

Zovirax has active ingredients of acyclovir sodium. It is often used in genital herpes. eHealthMe is studying from 9,031 Zovirax users. Check the latest studies of Zovirax.



On Jul, 14, 2026

36 people who take Risperdal and Zovirax together, and have interactions are studied.

Risperdal and Zovirax drug interactions.

What are the common drug interactions of Risperdal and Zovirax, by gender? *:

female:

  1. Pleural effusion (water on the lungs)
  2. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  3. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  4. Psychotic disorder
  5. Renal impairment (severely reduced kidney function)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Abnormal behaviour
  8. Anger
  9. Anxiety
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

  1. Anxiety
  2. Back pain
  3. Pain
  4. Renal failure acute (rapid kidney dysfunction)
  5. Abdominal pain upper
  6. Abscess (pus)
  7. Allodynia (a condition in which pain is caused by a stimulus that does not normally elicit pain)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Ankle fracture
  10. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)

What are the common drug interactions of Risperdal and Zovirax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hypertriglyceridaemia (excess of triglycerides in the blood)
  2. Agitation (state of anxiety or nervous excitement)

20-29:

  1. Altered state of consciousness (altered state of mind)
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Cyst (a closed sac)
  4. Cytomegalovirus viraemia (cytomegalo virus in blood stream)
  5. Hyperglycaemia (high blood sugar)
  6. Pleural effusion (water on the lungs)
  7. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
  8. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  9. Renal impairment (severely reduced kidney function)
  10. White blood cell count decreased

30-39:

  1. Asthma
  2. Bulimia nervosa (eating disorder characterized by recurrent binge eating, followed by compensatory behaviours)
  3. Drug abuse
  4. Drug dependence
  5. Dysthymic disorder (mild chronic depression disorder)
  6. Facial palsy (paralysis of face nerve)
  7. Mania (a state of abnormally elevated or irritable mood)
  8. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  9. Neutropenia (an abnormally low number of neutrophils)
  10. Obesity (having too much body fat)

40-49:

  1. Fall
  2. Agitation (state of anxiety or nervous excitement)
  3. Blood glucose increased
  4. Death
  5. Depressed level of consciousness
  6. Gait disturbance
  7. Psychotic disorder
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  9. Abnormal behaviour
  10. Anger

50-59:

  1. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Cough
  4. Cyst (a closed sac)
  5. Cystitis (inflammation of the wall of the bladder)
  6. Depression
  7. Diarrhoea
  8. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  9. Dyspnoea exertional (breathlessness or shortness of breath)
  10. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

60+:

  1. Sepsis (a severe blood infection that can lead to organ failure and death)
  2. Blood lactate dehydrogenase increased
  3. Platelet count decreased
  4. Renal failure (kidney dysfunction)
  5. Subcutaneous haematoma (collection of blood outside the blood vessels on the skin)
  6. Venoocclusive liver disease (small veins in the liver are obstructed)
  7. Vomiting
  8. White blood cell count increased
  9. Abdominal pain
  10. Accident

What are the existing conditions these people have? *

  1. Depression: 8 people, 22.22%
  2. Insomnia (sleeplessness): 7 people, 19.44%
  3. Herpes Zoster: 5 people, 13.89%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 11.11%
  5. Pain: 4 people, 11.11%
  6. Stress And Anxiety: 4 people, 11.11%
  7. Agitation (state of anxiety or nervous excitement): 3 people, 8.33%
  8. Constipation: 3 people, 8.33%
  9. Metastases To Bone (cancer spreads to bone): 3 people, 8.33%
  10. Lymphoma (cancer that begins in immune system cells): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Risperdal and Zovirax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Risperdal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zovirax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperdal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zovirax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risperidone and acyclovir sodium (the active ingredients of Risperdal and Zovirax, respectively), and Risperdal and Zovirax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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