Risperidone and Catapres drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperidone (risperidone) and Catapres (clonidine hydrochloride). Common drug interactions include hypotension among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Risperidone and Catapres. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

On Jul, 18, 2026

28 people who take Risperidone and Catapres together, and have interactions are studied.

Risperidone and Catapres drug interactions.

What are the common drug interactions of Risperidone and Catapres, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Agitation (state of anxiety or nervous excitement)
Hallucination (an experience involving the perception of something not present)
Coma (state of unconsciousness lasting more than six hours)
Withdrawal hypertension (low blood pressure due to nicotine withdrawal)
Lymphocyte count decreased
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Monocyte count increased
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Abnormal behaviour

male:

Aggression
Head injury
Confusional state
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Emotional disorder
Eosinophil count increased
Eye irritation
Facial bones fracture (bone fracture of face)
Fall

What are the common drug interactions of Risperidone and Catapres, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Agitation (state of anxiety or nervous excitement)
Hallucination (an experience involving the perception of something not present)
Somnolence (a state of near-sleep, a strong desire for sleep)
Dyskinesia (abnormality or impairment of voluntary movement)
Galactorrhoea (secretion of breast milk in men)
Hyperprolactinaemia (abnormally high levels of prolactin in the blood)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Coma (state of unconsciousness lasting more than six hours)
Lymphocyte count decreased
Monocyte count increased

10-19:

Withdrawal hypertension (low blood pressure due to nicotine withdrawal)
Hypotension (abnormally low blood pressure)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)

20-29:

Head injury
Aggression
Agitation (state of anxiety or nervous excitement)
Abnormal behaviour
Anger
Bone pain
Brain injury
Bruxism (habitual grinding of the teeth, typically during sleep)
Cardiotoxicity (damage to the heart muscle)
Clavicle fracture

30-39:

Anaemia (lack of blood)
Back pain
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

40-49:

Diarrhoea

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Chronic kidney disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depressed level of consciousness
Emotional distress
Encephalopathy (functioning of the brain is affected by some agent or condition)
Haematocrit decreased
Haemoglobin decreased
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hyporeflexia (a condition of below normal or absent reflexes)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 6 people, 21.43%
Insomnia (sleeplessness): 4 people, 14.29%
Stress And Anxiety: 3 people, 10.71%
Psychotic Disorder: 3 people, 10.71%
Psychomotor Hyperactivity (feelings of extreme restlessness): 3 people, 10.71%
Pain: 3 people, 10.71%
Mood Swings (an extreme or rapid change in mood): 3 people, 10.71%
Diabetes: 3 people, 10.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.14%
Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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