Risperidone and Emla drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperidone (risperidone) and Emla (lidocaine; prilocaine). Common drug interactions include urinary tract infection among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Risperidone and Emla. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

What is Emla?

Emla has active ingredients of lidocaine; prilocaine. eHealthMe is studying from 5,276 Emla users. Check the latest studies of Emla.



On Jul, 12, 2026

21 people who take Risperidone and Emla together, and have interactions are studied.

Risperidone and Emla drug interactions.

What are the common drug interactions of Risperidone and Emla, by gender? *:

female:

  1. Urinary tract infection
  2. Urticaria (rash of round, red welts on the skin that itch intensely)
  3. Acute respiratory distress syndrome
  4. Blood bilirubin increased
  5. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  6. Hypotension (abnormally low blood pressure)
  7. Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)
  8. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  9. Apnoea (suspension of external breathing)
  10. Biliary dilatation

male:

  1. Cough
  2. Nausea (feeling of having an urge to vomit)
  3. Ear infection
  4. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  5. Eczema eyelids (patches of skin become rough and inflamed, with itching and bleeding blisters on eyelid)
  6. Hallucination, auditory (perceiving sounds without auditory stimulus)
  7. Impulse-control disorder
  8. Lung neoplasm (tumour of lung)
  9. Lymphadenopathy (disease or enlargement of lymph nodes)
  10. Lymphoma (cancer that begins in immune system cells)

What are the common drug interactions of Risperidone and Emla, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Nausea (feeling of having an urge to vomit)
  2. Anger
  3. Anxiety
  4. Attention deficit/hyperactivity disorder
  5. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  6. B-cell lymphoma (blood cancer affecting b cells)
  7. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  8. Conjunctivitis (pink eye)
  9. Cough
  10. Ear infection

10-19:

  1. Rhinovirus infection
  2. Staphylococcal infection (an infection with staphylococcus bacteria)
  3. Acute respiratory distress syndrome
  4. Blood bilirubin increased
  5. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  6. Hypotension (abnormally low blood pressure)
  7. Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)
  8. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  9. Asthenia (weakness)
  10. Cold sweat

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Confusional state
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Blood lactate dehydrogenase increased
  4. Cardiac failure congestive
  5. Catatonia (unresponsive to external stimuli)
  6. Chest pain
  7. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  8. Cough
  9. Death
  10. Delirium (wild excitement)

What are the existing conditions these people have? *

  1. Pain: 8 people, 38.10%
  2. Nausea (feeling of having an urge to vomit): 8 people, 38.10%
  3. Agitation (state of anxiety or nervous excitement): 7 people, 33.33%
  4. Cough: 7 people, 33.33%
  5. High Blood Pressure: 6 people, 28.57%
  6. Dry Skin: 6 people, 28.57%
  7. Sedation: 5 people, 23.81%
  8. Heavy Or Prolong Menstrual Bleeding: 4 people, 19.05%
  9. Anaemia (lack of blood): 4 people, 19.05%
  10. Angiopathy (generic term for a disease of the blood vessels): 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Risperidone and Emla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Risperidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Emla:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Emla and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risperidone and lidocaine; prilocaine (the active ingredients of Risperidone and Emla, respectively), and Risperidone and Emla (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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