Risperidone and Sensipar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperidone (risperidone) and Sensipar (cinacalcet hydrochloride). Common drug interactions include anhedonia among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Risperidone and Sensipar. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

What is Sensipar?

Sensipar has active ingredients of cinacalcet hydrochloride. It is often used in hyperparathyroidism secondary. eHealthMe is studying from 46,034 Sensipar users. Check the latest studies of Sensipar.



On Jul, 25, 2026

18 people who take Risperidone and Sensipar together, and have interactions are studied.

Risperidone and Sensipar drug interactions.

What are the common drug interactions of Risperidone and Sensipar, by gender? *:

female:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Hospitalisation
  4. Hypoglycaemia (deficiency of glucose in the bloodstream)
  5. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  6. Pain
  7. Anger
  8. Chronic kidney disease
  9. Drug eruption (adverse drug reaction of the skin)
  10. Emotional distress

male:

  1. Renal failure (kidney dysfunction)
  2. Abdominal pain
  3. Fungaemia (fungi circulate in the blood)
  4. Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
  5. Hypersensitivity
  6. Hypotension (abnormally low blood pressure)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Multi-organ failure (multisystem organ failure)
  9. Necrosis (the death of body tissue)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

What are the common drug interactions of Risperidone and Sensipar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  4. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  5. Injury
  6. Joint range of motion decreased (disease of joint movement)
  7. Joint stiffness
  8. Muscle atrophy (a decrease in the mass of the muscle)
  9. Pain
  10. Skin induration (an abnormally hard spot or area on the skin)

50-59:

  1. Hospitalisation
  2. Hypoglycaemia (deficiency of glucose in the bloodstream)
  3. Anger
  4. Drug eruption (adverse drug reaction of the skin)
  5. Hand-foot-and-mouth disease
  6. Hypersensitivity
  7. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  8. Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
  9. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

60+:

  1. Renal failure (kidney dysfunction)
  2. Abdominal pain
  3. Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
  4. Hypersensitivity
  5. Hypotension (abnormally low blood pressure)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Multi-organ failure (multisystem organ failure)
  8. Necrosis (the death of body tissue)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Brain: 2 people, 11.11%
  2. Multiple Myeloma (cancer of the plasma cells): 2 people, 11.11%
  3. Chronic Kidney Disease: 2 people, 11.11%
  4. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 5.56%
  5. Medical Device Complication: 1 person, 5.56%
  6. Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 1 person, 5.56%
  7. Hiv Infection: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Risperidone and Sensipar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Risperidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sensipar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sensipar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risperidone and cinacalcet hydrochloride (the active ingredients of Risperidone and Sensipar, respectively), and Risperidone and Sensipar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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