Risperidone and Tradjenta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Risperidone (risperidone) and Tradjenta (linagliptin). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Risperidone and Tradjenta. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.
What is Risperidone?
Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.
What is Tradjenta?
Tradjenta has active ingredients of linagliptin. It is often used in diabetes. eHealthMe is studying from 9,987 Tradjenta users. Check the latest studies of Tradjenta.
39 people who take Risperidone and Tradjenta together, and have interactions are studied.

What are the common drug interactions of Risperidone and Tradjenta, by gender? *:
female:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Death
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Renal tubular necrosis (death of kidney tubules)
- Cervix carcinoma (cancer of cervix)
- Anxiety
- Asthenia (weakness)
- Cardiac failure congestive
- Drug ineffective
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Blood glucose increased
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Emotional distress
- Osteoporosis (bones weak and more likely to break)
- Pain
- Pruritus (severe itching of the skin)
What are the common drug interactions of Risperidone and Tradjenta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Chronic kidney disease
- Dermatillomania (skin picking disorders)
- Increased appetite
- Renal failure (kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
40-49:
- Renal failure (kidney dysfunction)
- Acute respiratory failure
- Cellulitis (infection under the skin)
- Pancreatitis necrotising (inflammation of the pancreas cause death of tissue in pancreas)
- Perirectal abscess
- Renal tubular necrosis (death of kidney tubules)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Septic shock (shock due to blood infection)
- Chronic kidney disease
50-59:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Asthenia (weakness)
- Bone density decreased
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Emotional disorder
- Emotional distress
- Gastric haemorrhage (bleeding stomach)
60+:
- Chronic kidney disease
- Death
- Asthenia (weakness)
- Cardiac failure congestive
- Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)
- Cough
- Dementia (madness)
- Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
- Drug ineffective
- Fall
What are the existing conditions these people have? *
- High Blood Pressure: 11 people, 28.21%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 28.21%
- Pain: 10 people, 25.64%
- Stress And Anxiety: 9 people, 23.08%
- High Blood Cholesterol: 8 people, 20.51%
- Type 2 Diabetes: 7 people, 17.95%
- Depression: 7 people, 17.95%
- Blood Pressure Abnormal: 6 people, 15.38%
- Psoriasis (immune-mediated disease that affects the skin): 4 people, 10.26%
- Infection: 4 people, 10.26%
* Approximation only. Some reports may have incomplete information.
Do you take Risperidone and Tradjenta?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Risperidone (72,175 reports)
- Tradjenta (9,987 reports)
Browse all drug interactions of Risperidone and Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Risperidone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tradjenta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Risperidone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tradjenta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on risperidone and linagliptin (the active ingredients of Risperidone and Tradjenta, respectively), and Risperidone and Tradjenta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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