Risperidone and Uptravi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperidone (risperidone) and Uptravi (selexipag). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Risperidone and Uptravi. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

What is Uptravi?

Uptravi has active ingredients of selexipag. eHealthMe is studying from 26,576 Uptravi users. Check the latest studies of Uptravi.



On Jul, 13, 2026

22 people who take Risperidone and Uptravi together, and have interactions are studied.

Risperidone and Uptravi drug interactions.

What are the common drug interactions of Risperidone and Uptravi, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Headache (pain in head)
  3. Atrial tachycardia (rhythm disturbance that arises in the atria)
  4. Pulmonary oedema (fluid accumulation in the lungs)
  5. Arthralgia (joint pain)
  6. Pain in jaw
  7. Cough
  8. Dyspnoea (difficult or laboured respiration)
  9. Hypotension (abnormally low blood pressure)
  10. Migraine (headache)

male:

n/a

What are the common drug interactions of Risperidone and Uptravi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Nausea (feeling of having an urge to vomit)
  2. Headache (pain in head)
  3. Chest pain
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Dizziness
  7. Cardiac failure
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Extrasystoles
  10. Atrial tachycardia (rhythm disturbance that arises in the atria)

40-49:

n/a

50-59:

  1. Pulmonary oedema (fluid accumulation in the lungs)

60+:

  1. Diarrhoea
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Migraine (headache)
  5. Cardiac failure
  6. Pulmonary hypertension (increase in blood pressure in the lung artery)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Cough

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 18 people, 81.82%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 27.27%
  3. Hypokalemia (low potassium): 6 people, 27.27%
  4. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 6 people, 27.27%
  5. Gastritis - Chronic (long lasting inflammation of stomach): 6 people, 27.27%
  6. Diabetes: 6 people, 27.27%
  7. Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 6 people, 27.27%
  8. Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 18.18%
  9. Right Ventricular Failure (right half of the heart fails to work): 2 people, 9.09%
  10. Hepatic Congestion (liver congestion): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Risperidone and Uptravi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Risperidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Uptravi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Uptravi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risperidone and selexipag (the active ingredients of Risperidone and Uptravi, respectively), and Risperidone and Uptravi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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