Risperidone and Vraylar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperidone (risperidone) and Vraylar (cariprazine hydrochloride). Common drug interactions include insomnia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Risperidone and Vraylar. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

What is Vraylar?

Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.

On Jul, 16, 2026

47 people who take Risperidone and Vraylar together, and have interactions are studied.

Risperidone and Vraylar drug interactions.

What are the common drug interactions of Risperidone and Vraylar, by gender? *:

female:

Insomnia (sleeplessness)
Affective disorder (mental disorder)
Anxiety
Weight increased
Blood prolactin increased
Decreased interest
Drug hypersensitivity
Facial spasm (involuntary muscle contractions face)
Fatigue (feeling of tiredness)
Hypersexuality

male:

Drug ineffective
Heart rate increased
Exostosis (formation of new bone on the surface of a bone)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastric disorder (disease of stomach)
Haematemesis (vomiting of blood)
Periodic limb movement disorder
Somnolence (a state of near-sleep, a strong desire for sleep)
Terminal state (the transitional states between life and biological death)
Therapeutic response unexpected

What are the common drug interactions of Risperidone and Vraylar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Brain injury
Completed suicide (act of taking one's own life)
Confusional state
Dystonia (abnormal muscle tone)
Euphoric mood (excessively happy but may become angry or irritable)
Hallucination (an experience involving the perception of something not present)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hypersexuality

20-29:

Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Delusion (a false belief or opinion)
Suicidal ideation
Adverse drug reaction
Anxiety
Blindness transient (sudden loss of vision)
Crying
Dysphagia (a condition in which swallowing is difficult or painful)
Facial spasm (involuntary muscle contractions face)
Fatigue (feeling of tiredness)

30-39:

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Asthenia (weakness)

40-49:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Bedridden
Blood prolactin increased
Mood altered (changes in mood)
Weight increased

50-59:

Drug ineffective
Therapeutic response unexpected
Heart rate increased
Insomnia (sleeplessness)

60+:

n/a

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 8 people, 17.02%
Insomnia (sleeplessness): 6 people, 12.77%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 10.64%
Sleep Disorder: 3 people, 6.38%
Psychotic Disorder: 3 people, 6.38%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 6.38%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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