Risperidone and Welchol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperidone (risperidone) and Welchol (colesevelam hydrochloride). Common drug interactions include abdominal distension among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Risperidone and Welchol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

What is Welchol?

Welchol has active ingredients of colesevelam hydrochloride. It is often used in high blood cholesterol. eHealthMe is studying from 11,309 Welchol users. Check the latest studies of Welchol.



On Jul, 11, 2026

13 people who take Risperidone and Welchol together, and have interactions are studied.

Risperidone and Welchol drug interactions.

What are the common drug interactions of Risperidone and Welchol, by gender? *:

female:

  1. Abdominal distension
  2. Abdominal pain
  3. Asthenia (weakness)
  4. Drug ineffective
  5. Fatigue (feeling of tiredness)
  6. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  7. Head injury
  8. Loss of consciousness
  9. Vomiting
  10. Weight decreased

male:

  1. Abdominal discomfort
  2. Blood potassium decreased
  3. Photophobia (extreme sensitivity to light)
  4. Prostate infection
  5. Renal failure (kidney dysfunction)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Urinary tract infection
  8. Visual impairment
  9. Vomiting
  10. Abnormal dreams

What are the common drug interactions of Risperidone and Welchol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Blood potassium decreased
  3. Cystitis (inflammation of the wall of the bladder)
  4. Diabetes mellitus inadequate control
  5. Drug dependence
  6. Fatigue (feeling of tiredness)
  7. Fear
  8. Headache (pain in head)
  9. Nausea (feeling of having an urge to vomit)
  10. Nervousness

50-59:

  1. Dehydration (dryness resulting from the removal of water)

60+:

  1. Abdominal distension
  2. Abdominal pain
  3. Biliary dilatation
  4. Blood alkaline phosphatase increased
  5. Blood creatinine increased
  6. Blood lactate dehydrogenase increased
  7. Cardiac failure congestive
  8. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  9. Chronic kidney disease
  10. Death

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 30.77%
  2. Fungal Infection: 3 people, 23.08%
  3. High Blood Pressure: 2 people, 15.38%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 15.38%
  5. Screaming (a long loud piercing cry): 1 person, 7.69%
  6. Agitation (state of anxiety or nervous excitement): 1 person, 7.69%
  7. Cardiac Disorder: 1 person, 7.69%
  8. Diarrhea: 1 person, 7.69%
  9. Fungaemia (fungi circulate in the blood): 1 person, 7.69%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Risperidone and Welchol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Risperidone and Welchol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Risperidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Welchol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Welchol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risperidone and colesevelam hydrochloride (the active ingredients of Risperidone and Welchol, respectively), and Risperidone and Welchol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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