Rituxan and Cablivi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rituxan (rituximab) and Cablivi (caplacizumab-yhdp). Common drug interactions include myalgia among females and platelet count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Rituxan and Cablivi. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Cablivi?

Cablivi has active ingredients of caplacizumab-yhdp. eHealthMe is studying from 1,147 Cablivi users. Check the latest studies of Cablivi.

On Jul, 28, 2026

41 people who take Rituxan and Cablivi together, and have interactions are studied.

What are the common drug interactions of Rituxan and Cablivi, by gender? *:

female:

Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pyrexia (fever)
Rash erythematous (redness of the skin)
Swelling
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)
Urinary tract infection
Weight increased

male:

Platelet count decreased
Drug hypersensitivity
Surgery
Arthralgia (joint pain)
Blood glucose increased
Blood pressure increased
Eosinophil count decreased
Fibrin d dimer increased
Haematocrit decreased
Haematuria (presence of blood in urine)

What are the common drug interactions of Rituxan and Cablivi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Epistaxis (bleed from the nose)
Rash

20-29:

Drug hypersensitivity
Epistaxis (bleed from the nose)
Balance disorder
Cough
Flushing (the warm, red condition of human skin)
Hypermetropia (abnormal condition in which vision for distant objects is better than for near objects)
Injection site pruritus (severe itching at injection site)
Injection site rash
Tremor (trembling or shaking movements in one or more parts of your body)
Arthralgia (joint pain)

30-39:

Epistaxis (bleed from the nose)
Blood pressure increased
Fatigue (feeling of tiredness)
Injection site bruising
Pain
Affect lability (emotional incontinence)
Anxiety
Back pain
Chills (felling of cold)
Depression

40-49:

Headache (pain in head)
Acne (skin problems that cause pimples)
Platelet count decreased
Anaemia (lack of blood)
Anaphylactic reaction (serious allergic reaction)
Fluid retention (an abnormal accumulation of fluid in the blood)
Hyperhidrosis (abnormally increased sweating)
Hyperphagia (an abnormal appetite for food)
Migraine (headache)
Nausea (feeling of having an urge to vomit)

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Platelet count decreased

60+:

Fatigue (feeling of tiredness)
Epistaxis (bleed from the nose)
Contusion (a type of hematoma of tissue in which capillaries)
Cushingoid (obesity and weakening of the muscles)
Decreased activity
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Infection
Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 35 people, 85.37%
Thrombotic Thrombocytopenic Purpura (a rare blood disorder characterized by clotting in small blood vessels of the body): 6 people, 14.63%

* Approximation only. Some reports may have incomplete information.

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