Rituxan and Imdur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rituxan (rituximab) and Imdur (isosorbide mononitrate). Common drug interactions include dry eye among females and hydronephrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Rituxan and Imdur. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.

On Jul, 12, 2026

38 people who take Rituxan and Imdur together, and have interactions are studied.

What are the common drug interactions of Rituxan and Imdur, by gender? *:

female:

Dry eye (lack of adequate tears)
Dyspnoea exertional (breathlessness or shortness of breath)
Eructation (release of gas from the digestive tract)
Fatigue (feeling of tiredness)
Febrile neutropenia (fever with reduced white blood cells)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Lymphadenopathy (disease or enlargement of lymph nodes)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Renal failure (kidney dysfunction)

male:

Hydronephrosis (water inside the kidney)
Abdominal pain
Mantle cell lymphoma (cancer of lymphocytes, a type of white blood cell)
Accelerated hypertension (significant hypertension)
Blood creatinine increased
Blood pressure decreased
Bone marrow failure
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Lymphadenopathy (disease or enlargement of lymph nodes)

What are the common drug interactions of Rituxan and Imdur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Arthralgia (joint pain)
Back pain
Diarrhoea
Dry eye (lack of adequate tears)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neck pain
Pyrexia (fever)
Abdominal pain upper

60+:

Thrombocytopenia (decrease of platelets in blood)
Therapeutic response decreased (less preventive response)
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Arterial restenosis (recurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow)
Asthma
Blood creatine phosphokinase increased
Blood creatinine increased
Blood pressure decreased

What are the existing conditions these people have? *

Lymphoma (cancer that begins in immune system cells): 6 people, 15.79%
Pain: 3 people, 7.89%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 7.89%
Vitamin B12 Deficiency: 2 people, 5.26%
Atrophic Vulvovaginitis (inflammation of the vulva): 2 people, 5.26%
Biotin Deficiency: 2 people, 5.26%
Chest Pain: 2 people, 5.26%
High Blood Pressure: 2 people, 5.26%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 5.26%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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