Rituxan and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rituxan (rituximab) and Reglan (metoclopramide hydrochloride). Common drug interactions include diarrhoea among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Rituxan and Reglan. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.



On Jul, 05, 2026

80 people who take Rituxan and Reglan together, and have interactions are studied.

Rituxan and Reglan drug interactions.

What are the common drug interactions of Rituxan and Reglan, by gender? *:

female:

  1. Diarrhoea
  2. Pyrexia (fever)
  3. Pneumonia
  4. Rash
  5. Fatigue (feeling of tiredness)
  6. Abdominal pain
  7. Infection
  8. Asthenia (weakness)
  9. Pain
  10. Sinusitis (inflammation of sinus)

male:

  1. Dyspnoea (difficult or laboured respiration)
  2. Death
  3. Bone disorder
  4. Chest pain
  5. Deformity (disfigurement)
  6. Discomfort
  7. Metastases to bone (cancer spreads to bone)
  8. Oedema peripheral (superficial swelling)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Pain in extremity

What are the common drug interactions of Rituxan and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Anaemia (lack of blood)
  3. Arthralgia (joint pain)
  4. Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
  5. Cerebral artery stenosis (hardening of brain blood vessels)
  6. Cerebral infarction (less blood supply to brain resulting tissue damage)
  7. Chest pain
  8. Chronic kidney disease
  9. Depression
  10. Dilated cardiomyopathy

30-39:

n/a

40-49:

  1. Diarrhoea
  2. Rash
  3. Abdominal pain
  4. Dyspnoea (difficult or laboured respiration)
  5. Abdominal pain upper
  6. Oral infection
  7. Vomiting
  8. Aphasia (damage to the parts of the brain that control language)
  9. Bedridden
  10. Blindness

50-59:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Cardiac failure congestive
  3. Dehydration (dryness resulting from the removal of water)
  4. Dyspnoea (difficult or laboured respiration)
  5. Hypokalaemia (low potassium)
  6. Leukocytosis (increased white blood cells)
  7. Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
  8. Pleural effusion (water on the lungs)
  9. Pneumonia
  10. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Asthenia (weakness)
  3. Hypertension (high blood pressure)
  4. Bone disorder
  5. Deformity (disfigurement)
  6. Dehydration (dryness resulting from the removal of water)
  7. Metastases to bone (cancer spreads to bone)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Pain in extremity
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 13 people, 16.25%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 15.00%
  3. Nausea (feeling of having an urge to vomit): 12 people, 15.00%
  4. Pain: 11 people, 13.75%
  5. Stress And Anxiety: 9 people, 11.25%
  6. High Blood Pressure: 7 people, 8.75%
  7. Bone Disorder: 7 people, 8.75%
  8. Prostate Cancer Metastatic: 7 people, 8.75%
  9. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 7.50%
  10. Indigestion: 6 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Rituxan and Reglan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rituxan and Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rituxan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Reglan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rituximab and metoclopramide hydrochloride (the active ingredients of Rituxan and Reglan, respectively), and Rituxan and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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