Robaxin and Adcirca drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Adcirca (tadalafil). Common drug interactions include confusional state among females.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Adcirca. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Adcirca?

Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 54,957 Adcirca users. Check the latest studies of Adcirca.

On Jul, 30, 2026

15 people who take Robaxin and Adcirca together, and have interactions are studied.

What are the common drug interactions of Robaxin and Adcirca, by gender? *:

female:

Confusional state
Headache (pain in head)
Epistaxis (bleed from the nose)
Feeling hot
Fungal infection
Hunger
Hyperhidrosis (abnormally increased sweating)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Infection
Loss of consciousness

male:

n/a

What are the common drug interactions of Robaxin and Adcirca, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Confusional state
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Somnolence (a state of near-sleep, a strong desire for sleep)
Abdominal pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Nausea (feeling of having an urge to vomit)
Septic shock (shock due to blood infection)
Vomiting
Cardiac failure acute
Cerebral infarction (less blood supply to brain resulting tissue damage)

40-49:

Headache (pain in head)
Cardiomegaly (increased size of heart than normal)
Feeling hot
Fungal infection
Hunger
Hyperhidrosis (abnormally increased sweating)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Infection
Loss of consciousness
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Gastric cancer (stomach cancer)
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)

60+:

Decreased appetite
Epistaxis (bleed from the nose)
Blood alkaline phosphatase increased
Confusional state
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic enzyme increased
Insomnia (sleeplessness)
International normalised ratio increased
Pain in jaw

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 60.00%
Stress And Anxiety: 3 people, 20.00%
Nausea And Vomiting: 3 people, 20.00%
Nausea (feeling of having an urge to vomit): 3 people, 20.00%
Diarrhea: 3 people, 20.00%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 2 people, 13.33%
Pain: 2 people, 13.33%
Swelling: 1 person, 6.67%
Subdural Haematoma (blood collects between the skull and the surface of the brain): 1 person, 6.67%
Dyspnea (difficult or laboured breathing): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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