Robaxin and Flector drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Flector (diclofenac epolamine). Common drug interactions include fibromyalgia among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Flector. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.



On Aug, 11, 2026

23 people who take Robaxin and Flector together, and have interactions are studied.

Robaxin and Flector drug interactions.

What are the common drug interactions of Robaxin and Flector, by gender? *:

female:

  1. Fibromyalgia (a long-term condition which causes pain all over the body)
  2. Migraine (headache)
  3. Weight decreased
  4. Balance disorder
  5. Depression
  6. Dizziness
  7. Vomiting
  8. Cholesterosis (abnormal deposition of cholesterol in tissues)
  9. Diarrhoea
  10. Influenza like illness

male:

  1. Drug hypersensitivity
  2. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Robaxin and Flector, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cholecystitis chronic (long lasting infection of gallbladder)
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Cholesterosis (abnormal deposition of cholesterol in tissues)
  4. Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
  5. Gallbladder disorder

30-39:

  1. Balance disorder
  2. Confusional state
  3. Crying
  4. Depressed mood
  5. Depression
  6. Dizziness
  7. Ear discomfort
  8. Headache (pain in head)
  9. Hypotension (abnormally low blood pressure)
  10. Loss of consciousness

40-49:

  1. Blood cholesterol increased
  2. Drug ineffective
  3. Fibromyalgia (a long-term condition which causes pain all over the body)
  4. Memory impairment
  5. Depression
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nausea (feeling of having an urge to vomit)
  8. Vomiting

50-59:

  1. Arthralgia (joint pain)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Decreased activity
  4. Diarrhoea
  5. Influenza like illness
  6. Migraine (headache)
  7. Myalgia (muscle pain)
  8. Sleep disorder
  9. Blood glucose increased
  10. Colitis (inflammation of colon)

60+:

  1. Anaemia (lack of blood)
  2. Balance disorder
  3. Pneumothorax traumatic
  4. Pruritus (severe itching of the skin)
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Rib fracture
  7. Swelling
  8. Thrombosis (formation of a blood clot inside a blood vessel)
  9. Venous thrombosis (blood clot (thrombus) that forms within a vein)
  10. Vomiting

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 5 people, 21.74%
  2. Depression: 5 people, 21.74%
  3. Sleep Disorder: 3 people, 13.04%
  4. Migraine (headache): 3 people, 13.04%
  5. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 13.04%
  6. Type 2 Diabetes: 2 people, 8.70%
  7. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.70%
  8. Pancreatitis Chronic (chronic inflammation of pancreas): 2 people, 8.70%
  9. Neck Pain: 2 people, 8.70%
  10. Joint Pain: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robaxin and Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robaxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flector and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methocarbamol and diclofenac epolamine (the active ingredients of Robaxin and Flector, respectively), and Robaxin and Flector (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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