Robaxin and Glucotrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Glucotrol (glipizide). Common drug interactions include depression among females and pancreatitis acute among males.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Glucotrol. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Glucotrol?

Glucotrol has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 20,322 Glucotrol users. Check the latest studies of Glucotrol.



On Jul, 26, 2026

57 people who take Robaxin and Glucotrol together, and have interactions are studied.

Robaxin and Glucotrol drug interactions.

What are the common drug interactions of Robaxin and Glucotrol, by gender? *:

female:

  1. Depression
  2. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  3. Erythema (redness of the skin)
  4. Fall
  5. Foot fracture
  6. Gait disturbance
  7. Hypoglycaemia (deficiency of glucose in the bloodstream)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Migraine (headache)
  10. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

  1. Pancreatitis acute (sudden inflammation of pancreas)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Drug dependence
  4. Drug ineffective
  5. Emotional distress
  6. Nausea (feeling of having an urge to vomit)
  7. Pain
  8. Adrenal mass
  9. Arthralgia (joint pain)
  10. Atelectasis (partial or complete collapse of the lung)

What are the common drug interactions of Robaxin and Glucotrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Chronic kidney disease
  3. Diabetic coma
  4. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  5. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  6. Hypertensive nephropathy (hypertensive renal disease)
  7. Pancreatic pseudocyst (collection of tissue and fluids that forms on pancreas)
  8. Pancreatitis acute (sudden inflammation of pancreas)
  9. Pancreatitis chronic (chronic inflammation of pancreas)
  10. Pancreatitis necrotising (inflammation of the pancreas cause death of tissue in pancreas)

40-49:

  1. Diabetes mellitus inadequate control
  2. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  3. Chronic kidney disease
  4. Renal failure (kidney dysfunction)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Blindness transient (sudden loss of vision)
  7. Blood cholesterol increased
  8. Dizziness
  9. Hyperglycaemia (high blood sugar)
  10. Hyperlipidaemia (presence of excess lipids in the blood)

50-59:

  1. Hyperglycaemia (high blood sugar)
  2. Hyperlipidaemia (presence of excess lipids in the blood)
  3. Intervertebral disc protrusion (spinal disc protrusion)
  4. Localised infection (infection at the single location)
  5. Neck pain
  6. Onychomycosis (fungal infection of the nail)
  7. Spinal osteoarthritis (joint cartilage loss in spine)
  8. Weight increased
  9. Cardiac failure congestive
  10. Depression

60+:

  1. Pancreatitis acute (sudden inflammation of pancreas)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Nausea (feeling of having an urge to vomit)
  4. Pain
  5. Pain in extremity
  6. Presyncope
  7. Pruritus (severe itching of the skin)
  8. Sinusitis (inflammation of sinus)
  9. Death
  10. Erythema (redness of the skin)

What are the existing conditions these people have? *

  1. High Blood Pressure: 19 people, 33.33%
  2. Pain: 17 people, 29.82%
  3. High Blood Cholesterol: 16 people, 28.07%
  4. Dyslipidaemia (abnormal amount of lipids): 13 people, 22.81%
  5. Type 2 Diabetes: 13 people, 22.81%
  6. Sinusitis (inflammation of sinus): 10 people, 17.54%
  7. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 10 people, 17.54%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 15.79%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 15.79%
  10. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robaxin and Glucotrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Glucotrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robaxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glucotrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on methocarbamol and glipizide (the active ingredients of Robaxin and Glucotrol, respectively), and Robaxin and Glucotrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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