Robaxin and Ocrevus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Ocrevus (ocrelizumab). Common drug interactions include cyst rupture among females and muscular weakness among males.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Ocrevus. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.



On Aug, 11, 2026

54 people who take Robaxin and Ocrevus together, and have interactions are studied.

Robaxin and Ocrevus drug interactions.

What are the common drug interactions of Robaxin and Ocrevus, by gender? *:

female:

  1. Cyst rupture (fluid leakage from sac)
  2. Decreased appetite
  3. Disturbance in attention
  4. Drug hypersensitivity
  5. Fatigue (feeling of tiredness)
  6. Fall
  7. Weight increased
  8. Pain in extremity
  9. Asthenia (weakness)
  10. Insomnia (sleeplessness)

male:

  1. Muscular weakness (muscle weakness)
  2. Breast cancer
  3. Chest pain
  4. Dyspnoea (difficult or laboured respiration)
  5. Fall
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Cellulitis (infection under the skin)
  8. Depression
  9. Fatigue (feeling of tiredness)
  10. Glucose urine present

What are the common drug interactions of Robaxin and Ocrevus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Breast abscess
  2. Cellulitis (infection under the skin)
  3. Depression
  4. Drug hypersensitivity
  5. Muscle tightness
  6. Vitamin d decreased

30-39:

  1. Memory impairment
  2. Fall
  3. Vision blurred
  4. Asthenia (weakness)
  5. Balance disorder
  6. Blindness unilateral
  7. Drug ineffective
  8. Fatigue (feeling of tiredness)
  9. Gait disturbance
  10. Hypersomnia (excessive daytime sleepiness (eds))

40-49:

  1. Fatigue (feeling of tiredness)
  2. Migraine (headache)
  3. Insomnia (sleeplessness)
  4. Pain in extremity
  5. Abdominal distension
  6. Agitation (state of anxiety or nervous excitement)
  7. Anger
  8. Asthenia (weakness)
  9. Bone pain
  10. Confusional state

50-59:

  1. General physical health deterioration (weak health status)
  2. Hepatic steatosis (fatty liver disease)
  3. Hepatomegaly (abnormal enlargement of the liver)
  4. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  5. Hyperglycaemia (high blood sugar)
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Intervertebral disc degeneration (spinal disc degeneration)
  8. Intervertebral disc displacement
  9. Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
  10. Muscular weakness (muscle weakness)

60+:

  1. Fatigue (feeling of tiredness)
  2. Neuralgia (pain in one or more nerves)
  3. Pain in extremity
  4. Urinary tract infection
  5. Weight increased
  6. Breast cancer
  7. Depression
  8. Glucose urine present
  9. Muscular weakness (muscle weakness)
  10. Nephrolithiasis (calculi in the kidneys)

What are the existing conditions these people have? *

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 24 people, 44.44%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 21 people, 38.89%
  3. Pain: 15 people, 27.78%
  4. Depression: 9 people, 16.67%
  5. Stress And Anxiety: 7 people, 12.96%
  6. Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 7 people, 12.96%
  7. Neuropathy Peripheral (surface nerve damage): 7 people, 12.96%
  8. Fatigue (feeling of tiredness): 6 people, 11.11%
  9. Insomnia (sleeplessness): 6 people, 11.11%
  10. Back Pain: 5 people, 9.26%

* Approximation only. Some reports may have incomplete information.

Do you take Robaxin and Ocrevus?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robaxin and Ocrevus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ocrevus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robaxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ocrevus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methocarbamol and ocrelizumab (the active ingredients of Robaxin and Ocrevus, respectively), and Robaxin and Ocrevus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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