Robaxin and Pravachol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Pravachol (pravastatin sodium). Common drug interactions include diabetes mellitus among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Pravachol. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Pravachol?

Pravachol has active ingredients of pravastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 24,382 Pravachol users. Check the latest studies of Pravachol.



On Jul, 26, 2026

84 people who take Robaxin and Pravachol together, and have interactions are studied.

Robaxin and Pravachol drug interactions.

What are the common drug interactions of Robaxin and Pravachol, by gender? *:

female:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Pleural effusion (water on the lungs)
  3. Pneumonia
  4. Acute respiratory failure
  5. Aphonia (inability to produce voice)
  6. Blood creatinine increased
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Depression
  9. Drug ineffective
  10. Headache (pain in head)

male:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Fall
  4. Nausea (feeling of having an urge to vomit)
  5. Pain in extremity
  6. Peripheral vascular disorder
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Tendonitis (a condition that causes pain and swelling of tendons)
  9. Testicular failure (testicles cannot produce sperm or male hormones)
  10. Trigger finger

What are the common drug interactions of Robaxin and Pravachol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Adverse event
  2. Benign prostatic hyperplasia (benign enlargement of the prostate)
  3. Blood glucose decreased
  4. Blood glucose increased
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Cystitis interstitial (unknown cause characterized by bladder pain)
  7. Diarrhoea
  8. Drug administration error
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

40-49:

  1. Pain
  2. Acute respiratory failure
  3. Asthenia (weakness)
  4. Diastolic dysfunction
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Generalised oedema (swelling all over the body)
  9. Hepatic lesion
  10. Hypertension (high blood pressure)

50-59:

  1. Inflammation
  2. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Neck pain
  5. Chronic kidney disease
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Nausea (feeling of having an urge to vomit)
  8. Headache (pain in head)
  9. Lacrimation increased
  10. Myalgia (muscle pain)

60+:

  1. Fall
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Blood creatinine increased
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Influenza
  7. Lactic acidosis (low ph in body tissues)
  8. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  9. Lower limb fracture
  10. Abdominal pain

What are the existing conditions these people have? *

  1. Pain: 19 people, 22.62%
  2. High Blood Pressure: 10 people, 11.90%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 10.71%
  4. Stress And Anxiety: 8 people, 9.52%
  5. Nausea (feeling of having an urge to vomit): 8 people, 9.52%
  6. Hypersensitivity: 8 people, 9.52%
  7. Cardiac Disorder: 8 people, 9.52%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 9.52%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 9.52%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 7 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robaxin and Pravachol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pravachol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robaxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pravachol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methocarbamol and pravastatin sodium (the active ingredients of Robaxin and Pravachol, respectively), and Robaxin and Pravachol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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