Robaxin and Sucralfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Sucralfate (sucralfate). Common drug interactions include headache among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Sucralfate. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Sucralfate?

Sucralfate has active ingredients of sucralfate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 17,548 Sucralfate users. Check the latest studies of Sucralfate.



On Jul, 21, 2026

50 people who take Robaxin and Sucralfate together, and have interactions are studied.

Robaxin and Sucralfate drug interactions.

What are the common drug interactions of Robaxin and Sucralfate, by gender? *:

female:

  1. Headache (pain in head)
  2. Nausea (feeling of having an urge to vomit)
  3. Cough
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Asthma
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Cystitis interstitial (unknown cause characterized by bladder pain)
  9. Dry skin
  10. Fluid retention (an abnormal accumulation of fluid in the blood)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Pain
  6. Allergy to metals
  7. Pruritus (severe itching of the skin)

What are the common drug interactions of Robaxin and Sucralfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Lip swelling
  2. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  3. Neuropathy peripheral (surface nerve damage)
  4. Thrombosis (formation of a blood clot inside a blood vessel)
  5. Weight gain poor
  6. Anxiety
  7. Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
  8. Arthralgia (joint pain)
  9. Arthropathy
  10. Balance disorder

50-59:

  1. Asthma
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Cystitis interstitial (unknown cause characterized by bladder pain)
  4. Inflammation
  5. Chronic kidney disease
  6. Hypersensitivity
  7. Intervertebral disc protrusion (spinal disc protrusion)
  8. Renal failure (kidney dysfunction)
  9. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  10. Vertigo

60+:

  1. Pain
  2. Head injury
  3. Decreased appetite
  4. Drug hypersensitivity
  5. Dyspnoea (difficult or laboured respiration)
  6. Emotional distress
  7. Fall
  8. Fluid retention (an abnormal accumulation of fluid in the blood)
  9. Headache (pain in head)
  10. Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 14.00%
  2. Pain: 7 people, 14.00%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 14.00%
  4. Stress And Anxiety: 6 people, 12.00%
  5. Depression: 6 people, 12.00%
  6. High Blood Cholesterol: 6 people, 12.00%
  7. Sleep Disorder: 4 people, 8.00%
  8. High Blood Pressure: 3 people, 6.00%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 6.00%
  10. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robaxin and Sucralfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robaxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sucralfate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robaxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sucralfate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methocarbamol and sucralfate (the active ingredients of Robaxin and Sucralfate, respectively), and Robaxin and Sucralfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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