Robinul and Flagyl drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Robinul (glycopyrrolate) and Flagyl (metronidazole). Common drug interactions include lethargy among females and cellulitis among males.
The phase IV clinical study analyzes what interactions people have when they take Robinul and Flagyl. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Robinul?
Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.
What is Flagyl?
Flagyl has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 25,897 Flagyl users. Check the latest studies of Flagyl.
29 people who take Robinul and Flagyl together, and have interactions are studied.

What are the common drug interactions of Robinul and Flagyl, by gender? *:
female:
- Lethargy (tiredness)
- Lung infection
- Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)
- Malignant neoplasm progression (cancer tumour came back)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Night sweats (sweating in night)
- Obesity (having too much body fat)
- Oxygen saturation decreased
- Pallor
male:
- Cellulitis (infection under the skin)
- Gas gangrene (bacterial infection that produces gas within tissues)
- Duodenal ulcer
- Gamma-glutamyltransferase increased
- Haemoglobin decreased
- Melaena (the passage of black, tarry stools)
- Tooth abscess (pus formation in tooth)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Genital abscess (build up of pus in genital)
- Infection
What are the common drug interactions of Robinul and Flagyl, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Duodenal ulcer
- Haemoglobin decreased
- Melaena (the passage of black, tarry stools)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Scoliosis (a medical condition in which a person's spine is curved from side to side)
20-29:
- Obesity (having too much body fat)
- Type 2 diabetes mellitus
30-39:
- Abdominal pain upper
- Clostridial infection (infectious conditions by clostridium bacteria)
- Haematochezia (passage of stools containing blood)
- Tinnitus (a ringing in the ears)
- Vomiting
- Weight decreased
- Blood alkaline phosphatase nos increased
- Gamma-glutamyltransferase increased
40-49:
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Arthralgia (joint pain)
- Cellulitis (infection under the skin)
- Cough
- Electrocardiogram abnormal
- Gas gangrene (bacterial infection that produces gas within tissues)
- Groin abscess (pus in groin)
- Groin pain
- Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx)
50-59:
- Vomiting
- Decreased activity
- Headache (pain in head)
- Malaise (a feeling of general discomfort or uneasiness)
- Myalgia (muscle pain)
- Abdominal pain
- Cellulitis (infection under the skin)
- Cholecystitis (infection of gallbladder)
- Gallbladder disorder
- Gas gangrene (bacterial infection that produces gas within tissues)
60+:
- Leukocytosis (increased white blood cells)
- Hypoxia (low oxygen in tissues)
- Aortic valve stenosis (narrowing of the aortic valve)
- Atelectasis (partial or complete collapse of the lung)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Coagulopathy (blood's ability to clot is impaired)
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
- Leukostasis (excessive number of white blood cells in blood)
- Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
What are the existing conditions these people have? *
- Pain: 7 people, 24.14%
- High Blood Pressure: 7 people, 24.14%
- Hypotension (abnormally low blood pressure): 5 people, 17.24%
- Stress And Anxiety: 5 people, 17.24%
- Diabetes: 5 people, 17.24%
- Toxoplasmosis (a parasitic disease caused by the protozoan toxoplasma gondii): 4 people, 13.79%
- Constipation: 4 people, 13.79%
- Diarrhea: 4 people, 13.79%
- Weight Decreased: 3 people, 10.34%
- Cardiac Disorder: 3 people, 10.34%
* Approximation only. Some reports may have incomplete information.
Do you take Robinul and Flagyl?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Robinul and Flagyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Robinul:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flagyl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Robinul and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flagyl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on glycopyrrolate and metronidazole (the active ingredients of Robinul and Flagyl, respectively), and Robinul and Flagyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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