Robinul and Restoril drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Robinul (glycopyrrolate) and Restoril (temazepam). Common drug interactions include bone disorder among females and haemoglobin decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Robinul and Restoril. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.
What is Robinul?
Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.
What is Restoril?
Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.
25 people who take Robinul and Restoril together, and have interactions are studied.

What are the common drug interactions of Robinul and Restoril, by gender? *:
female:
- Bone disorder
- Depression
- Dizziness
- Fall
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Pain
- Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
- Adnexa uteri mass (ovarian cysts)
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
male:
- Haemoglobin decreased
- Agitation (state of anxiety or nervous excitement)
- Blood glucose decreased
- Blood pressure fluctuation
- Blood urea increased
- Bone disorder
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Cataract (clouding of the lens inside the eye)
- Confusional state
- Constipation
What are the common drug interactions of Robinul and Restoril, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Erythema (redness of the skin)
- Haemoglobin decreased
- Haemorrhage (bleeding)
- Oedema (fluid collection in tissue)
40-49:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
50-59:
- Adrenal mass
- Agitation (state of anxiety or nervous excitement)
- Back pain
- Chest pain
- Chronic kidney disease
- Deafness unilateral
- Dementia (madness)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diplopia (double vision)
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
60+:
- Anxiety
- Arthralgia (joint pain)
- Oedema peripheral (superficial swelling)
- Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
- Weight decreased
- Agitation (state of anxiety or nervous excitement)
- Alanine aminotransferase decreased
- Asthenia (weakness)
- Back pain
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
What are the existing conditions these people have? *
- Prostate Cancer: 12 people, 48.00%
- Metastases To Bone (cancer spreads to bone): 12 people, 48.00%
- Pain: 2 people, 8.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Robinul and Restoril?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Robinul and Restoril:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Robinul:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Restoril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Robinul and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restoril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
- D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on glycopyrrolate and temazepam (the active ingredients of Robinul and Restoril, respectively), and Robinul and Restoril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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