Robinul and Risperdal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robinul (glycopyrrolate) and Risperdal (risperidone). Common drug interactions include atrioventricular block complete among females and dystonia among males.

The phase IV clinical study analyzes what interactions people have when they take Robinul and Risperdal. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.



On Jul, 07, 2026

15 people who take Robinul and Risperdal together, and have interactions are studied.

Robinul and Risperdal drug interactions.

What are the common drug interactions of Robinul and Risperdal, by gender? *:

female:

  1. Atrioventricular block complete (heart block complete)
  2. Vomiting
  3. Abdominal discomfort
  4. Abdominal pain
  5. Agitation (state of anxiety or nervous excitement)
  6. Bradycardia (abnormally slow heart action)
  7. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  8. Chest pain
  9. Constipation
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

male:

  1. Dystonia (abnormal muscle tone)
  2. Hallucination (an experience involving the perception of something not present)
  3. Erythema (redness of the skin)
  4. Fatigue (feeling of tiredness)
  5. Hyperpyrexia (extremely high fever)
  6. Hypertension (high blood pressure)
  7. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  8. Ill-defined disorder
  9. Multiple injuries
  10. Pain

What are the common drug interactions of Robinul and Risperdal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Agitation (state of anxiety or nervous excitement)
  2. Loss of consciousness
  3. Vomiting

10-19:

n/a

20-29:

  1. Obesity (having too much body fat)
  2. Type 2 diabetes mellitus

30-39:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Gallbladder disorder

40-49:

  1. Abdominal pain
  2. Blood creatine phosphokinase increased
  3. Constipation
  4. Dyspepsia (indigestion)
  5. Gastrointestinal mucosal necrosis (damage of mucous membrane in gastrointestinal tract)
  6. Gastrointestinal perforation (hole in the digestive tract)
  7. Hyperpyrexia (extremely high fever)
  8. Hypertension (high blood pressure)
  9. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
  10. Hypotension (abnormally low blood pressure)

50-59:

  1. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  2. Diarrhoea
  3. Erythema (redness of the skin)
  4. Fatigue (feeling of tiredness)
  5. Pain
  6. Pain of skin
  7. Vomiting
  8. Weight decreased

60+:

  1. Atrioventricular block complete (heart block complete)
  2. Hallucination (an experience involving the perception of something not present)
  3. Chest pain
  4. Nodal rhythm (40-50 beats per minute)
  5. Urinary tract infection
  6. Dystonia (abnormal muscle tone)
  7. Locked-in syndrome (a condition in which a patient is aware and awake but cannot move or communicate verbally due to complete paralysis)
  8. Nightmare (unpleasant dream)
  9. Paralysis
  10. Tardive dyskinesia (a disorder that involves involuntary movements)

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 20.00%
  2. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 6.67%
  3. Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 6.67%
  4. Stress And Anxiety: 1 person, 6.67%
  5. Sleep Disorder: 1 person, 6.67%
  6. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.67%
  7. Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 1 person, 6.67%
  8. Parkinson's Disease: 1 person, 6.67%
  9. Mood Swings (an extreme or rapid change in mood): 1 person, 6.67%
  10. Leukaemia (blood or bone marrow cancer): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Robinul and Risperdal?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robinul and Risperdal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Risperdal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robinul and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperdal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glycopyrrolate and risperidone (the active ingredients of Robinul and Risperdal, respectively), and Robinul and Risperdal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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