Robitussin and Ancef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robitussin (guaifenesin) and Ancef (cefazolin sodium). Common drug interactions include drug exposure during pregnancy among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Robitussin and Ancef. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Ancef?

Ancef has active ingredients of cefazolin sodium. eHealthMe is studying from 3,292 Ancef users. Check the latest studies of Ancef.

On Jul, 16, 2026

16 people who take Robitussin and Ancef together, and have interactions are studied.

What are the common drug interactions of Robitussin and Ancef, by gender? *:

female:

Drug exposure during pregnancy
Kidney malformation (kidneys that have not developed properly)
Pericardial effusion (fluid around the heart)
Asthenia (weakness)
Cardiac tamponade (fluid accumulates in heart covering)
Dyspnoea at rest (difficult or laboured breathing during rest)
Dyspnoea exertional (breathlessness or shortness of breath)
Failure to thrive (inadequate weight gain and physical growth in children)
Feeding disorder (when children refuse to eat certain food groups)
General physical health deterioration (weak health status)

male:

Asthenia (weakness)
Chest discomfort
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Night sweats (sweating in night)
Productive cough
Pruritus (severe itching of the skin)
Pseudomonas test positive
Pyrexia (fever)
Secretion discharge
Sputum discoloured

What are the common drug interactions of Robitussin and Ancef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthenia (weakness)
Chest discomfort
Chest pain
Cough
Decreased appetite
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

40-49:

n/a

50-59:

Muscle haemorrhage (bleeding in muscle)
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Pericardial effusion (fluid around the heart)
Acute respiratory distress syndrome
Feeding disorder (when children refuse to eat certain food groups)
General physical health deterioration (weak health status)
Glomerular filtration rate decreased
Platelet count decreased
Pleural effusion (water on the lungs)
Productive cough
Renal failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Depression: 9 people, 56.25%
Wheezing (a high-pitched whistling sound made while you breath): 6 people, 37.50%
Migraine Without Aura (headache without neurological problems): 6 people, 37.50%
Bacterial Infection: 6 people, 37.50%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 6 people, 37.50%
Constipation: 6 people, 37.50%
Cough: 6 people, 37.50%
Cystic Fibrosis (disease of the secretary glands): 6 people, 37.50%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 6 people, 37.50%
Cystic Fibrosis Pancreatic (fibrosis with cyst in the pancreas): 6 people, 37.50%

* Approximation only. Some reports may have incomplete information.

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