Robitussin and Ofev drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robitussin (guaifenesin) and Ofev (nintedanib esylate). Common drug interactions include diarrhoea among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Robitussin and Ofev. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Ofev?

Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.

On Jul, 19, 2026

18 people who take Robitussin and Ofev together, and have interactions are studied.

What are the common drug interactions of Robitussin and Ofev, by gender? *:

female:

Diarrhoea
Vomiting
Cough
Decreased appetite
Nausea (feeling of having an urge to vomit)
Weight decreased
Dyspnoea (difficult or laboured respiration)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Asthenia (weakness)
Cataract (clouding of the lens inside the eye)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dizziness
Dyspnoea (difficult or laboured respiration)
Heart injury
Memory impairment
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Stent placement
Chest pain
Cough
Decreased appetite

What are the common drug interactions of Robitussin and Ofev, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Arterial rupture
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Stent placement
Cough
Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Productive cough
Wheezing (a high-pitched whistling sound made while you breath)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Dizziness
Dyspepsia (indigestion)
Hypoaesthesia (reduced sense of touch or sensation)
Abdominal discomfort
Gout (uric acid crystals building up in the body)
Migraine (headache)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Decreased appetite
Heart injury

60+:

Diarrhoea
Vomiting
Pneumonia
Dyspnoea exertional (breathlessness or shortness of breath)
Eating disorder
Epistaxis (bleed from the nose)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Nasopharyngitis (inflammation of the nasopharynx)
Productive cough
Abdominal discomfort

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 16 people, 88.89%
Depression: 3 people, 16.67%
Cystic Fibrosis (disease of the secretary glands): 3 people, 16.67%
Diabetes: 1 person, 5.56%
Cough: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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