Rocaltrol and Isosorbide mononitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rocaltrol (calcitriol) and Isosorbide mononitrate (isosorbide mononitrate). Common drug interactions include lethargy among females and cognitive disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Rocaltrol and Isosorbide mononitrate. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Rocaltrol?

Rocaltrol has active ingredients of calcitriol. It is often used in hypoparathyroidism. eHealthMe is studying from 7,562 Rocaltrol users. Check the latest studies of Rocaltrol.

What is Isosorbide mononitrate?

Isosorbide mononitrate has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 26,858 Isosorbide mononitrate users. Check the latest studies of Isosorbide mononitrate.

On Jul, 16, 2026

31 people who take Rocaltrol and Isosorbide mononitrate together, and have interactions are studied.

Rocaltrol and Isosorbide mononitrate drug interactions.

What are the common drug interactions of Rocaltrol and Isosorbide Mononitrate, by gender? *:

female:

Lethargy (tiredness)
Ligament sprain (ligament stretched)
Localised infection (infection at the single location)
Malaise (a feeling of general discomfort or uneasiness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nasopharyngitis (inflammation of the nasopharynx)
Oral infection
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Pleural effusion (water on the lungs)

male:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depressed level of consciousness
General physical health deterioration (weak health status)
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)
Joint stiffness
Mobility decreased (ability to move is reduced)
Muscle atrophy (a decrease in the mass of the muscle)
Muscle disorder (muscle disease)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the common drug interactions of Rocaltrol and Isosorbide Mononitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Urinary tract infection
Abdominal pain
Back pain
Drug level increased
Dry gangrene (diminished blood supply due to vascular problems)
Haemoglobin decreased
Hypertensive encephalopathy (neurological dysfunction induced by malignant hypertension)
Localised infection (infection at the single location)
Renal hypertension (high blood pressure caused by the kidneys hormonal response)

60+:

Nausea (feeling of having an urge to vomit)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Deformity (disfigurement)
Diarrhoea
Dry mouth
Emotional distress
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
General physical health deterioration (weak health status)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 19.35%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 19.35%
Pain: 4 people, 12.90%
Acute Myocardial Infarction (acute heart attack): 3 people, 9.68%
Asthma: 3 people, 9.68%
Renal Osteodystrophy (a bone disease occurs when the kidneys fail to maintain the proper levels of calcium and phosphorus in the blood): 3 people, 9.68%
Gout (uric acid crystals building up in the body): 2 people, 6.45%
Calcium Deficiency (lack of calcium): 2 people, 6.45%
Cardiac Disorder: 2 people, 6.45%
Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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