Rocephin and Dapsone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Dapsone (dapsone). Common drug interactions include haemoglobin decreased among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Rocephin and Dapsone. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Dapsone?

Dapsone has active ingredients of dapsone. It is often used in dermatitis herpetiformis. eHealthMe is studying from 11,732 Dapsone users. Check the latest studies of Dapsone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

22 people who take Rocephin and Dapsone together, and have interactions are studied.

What are the common drug interactions of Rocephin and Dapsone, by gender? *:

female:

Haemoglobin decreased
Chronic kidney disease
Dysphagia (a condition in which swallowing is difficult or painful)
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Skin exfoliation (removal of the oldest dead skin cells)
Urticaria (rash of round, red welts on the skin that itch intensely)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anaemia (lack of blood)
Back pain
Chest pain
Cryptococcosis (potentially fatal fungal disease)
Death
Diarrhoea
Dysuria (painful or difficult urination)
Groin pain

What are the common drug interactions of Rocephin and Dapsone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pain
Chest pain
Pain in extremity
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Drug ineffective
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)

40-49:

Sepsis (a severe blood infection that can lead to organ failure and death)
Chronic kidney disease
Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
Haematuria (presence of blood in urine)
Haemoglobin decreased
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Skin infection
Alkalosis

50-59:

Hyperglycaemia (high blood sugar)
Meningitis pneumococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
Pleuritic pain
Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
Pyrexia (fever)
Rash
Sinusitis (inflammation of sinus)
Thrombocytopenia (decrease of platelets in blood)
Viral infection
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Aphasia (damage to the parts of the brain that control language)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Injection site reaction
Methaemoglobinaemia (a disorder characterized by the presence of a higher than normal level of methemoglobin in blood)
Necrosis (the death of body tissue)
Skin discolouration (change of skin colour)
Swelling

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 13.64%
Idiopathic Urticaria (allergic reactions, presence of hives with unknown cause): 2 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.09%
Hiv Infection: 2 people, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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