Rocephin and Rasilez drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Rasilez (aliskiren hemifumarate). Common drug interactions include iron deficiency anaemia among females and renal tubular disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Rocephin and Rasilez. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Rocephin?
Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.
What is Rasilez?
Rasilez has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 6,001 Rasilez users. Check the latest studies of Rasilez.
20 people who take Rocephin and Rasilez together, and have interactions are studied.

What are the common drug interactions of Rocephin and Rasilez, by gender? *:
female:
- Iron deficiency anaemia
- Mania (a state of abnormally elevated or irritable mood)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Rhinitis allergic (inflammation of the nasal airways due to allergy)
- Nasopharyngitis (inflammation of the nasopharynx)
- Tooth infection
- Toothache (tooth pain)
- Colon cancer metastatic (cancer of colon spreads to other part of body)
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Post procedural haemorrhage (post procedural bleeding)
male:
- Renal tubular disorder (disease of kidney tubules)
- Renal failure acute (rapid kidney dysfunction)
What are the common drug interactions of Rocephin and Rasilez, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
- Conjunctivitis allergic (inflammation of the conjunctiva due to allergy)
- Gastroenteritis (inflammation of stomach and intestine)
- Gingivitis (inflammation of gums)
- Herpes zoster
- Influenza
- Insomnia (sleeplessness)
- Iron deficiency anaemia
- Mania (a state of abnormally elevated or irritable mood)
30-39:
n/a
40-49:
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Post procedural haemorrhage (post procedural bleeding)
- Thrombocytopenia (decrease of platelets in blood)
- Pyrexia (fever)
50-59:
n/a
60+:
- Colon cancer metastatic (cancer of colon spreads to other part of body)
- Renal tubular disorder (disease of kidney tubules)
- Toxic skin eruption (skin breakdown due to toxic substance)
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Blood iron decreased
- Bronchopneumopathy
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Enterocolitis infectious
- Metastases to liver (cancer spreads to liver)
- Metastases to lung (cancer spreads to lung)
What are the existing conditions these people have? *
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 55.00%
- Conjunctivitis Allergic (inflammation of the conjunctiva due to allergy): 7 people, 35.00%
- Mania (a state of abnormally elevated or irritable mood): 7 people, 35.00%
- Herpes Zoster: 7 people, 35.00%
- Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 35.00%
- Insomnia (sleeplessness): 7 people, 35.00%
- Iron Deficiency Anaemia: 7 people, 35.00%
- Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 7 people, 35.00%
- Gingivitis (inflammation of gums): 7 people, 35.00%
- Gastroenteritis (inflammation of stomach and intestine): 7 people, 35.00%
* Approximation only. Some reports may have incomplete information.
Do you take Rocephin and Rasilez?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rocephin and Rasilez:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rasilez:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rocephin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rasilez and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ceftriaxone sodium and aliskiren hemifumarate (the active ingredients of Rocephin and Rasilez, respectively), and Rocephin and Rasilez (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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