Rocephin and Thalomid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Thalomid (thalidomide). Common drug interactions include abdominal distension among females and white blood cell count decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Rocephin and Thalomid. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Rocephin?
Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.
What is Thalomid?
Thalomid has active ingredients of thalidomide. It is often used in multiple myeloma. eHealthMe is studying from 38,099 Thalomid users. Check the latest studies of Thalomid.
18 people who take Rocephin and Thalomid together, and have interactions are studied.

What are the common drug interactions of Rocephin and Thalomid, by gender? *:
female:
- Abdominal distension
- Dehydration (dryness resulting from the removal of water)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Pain
- Renal failure acute (rapid kidney dysfunction)
- Swelling face
- Fluid overload (too much fluid in the blood)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
male:
- White blood cell count decreased
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
- Neutropenia (an abnormally low number of neutrophils)
- Renal failure chronic (long lasting kidney dysfunction)
- Subdural haematoma (blood collects between the skull and the surface of the brain)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- White blood cells urine positive
- Anaemia (lack of blood)
What are the common drug interactions of Rocephin and Thalomid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Abdominal distension
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Pain
- Swelling face
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Haemoglobin decreased
- Hyperglycaemia (high blood sugar)
- Meningitis pneumococcal (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
- Pleuritic pain
60+:
- White blood cell count decreased
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
- Hypertension (high blood pressure)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
- Neutropenia (an abnormally low number of neutrophils)
- Renal failure chronic (long lasting kidney dysfunction)
- Subdural haematoma (blood collects between the skull and the surface of the brain)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
What are the existing conditions these people have? *
- Angiopathy (generic term for a disease of the blood vessels): 2 people, 11.11%
- Hereditary Angioedema (recurrent episodes of severe swelling): 2 people, 11.11%
- Musculoskeletal Chest Pain (pain in chest muscle or nerve or bones): 1 person, 5.56%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.56%
- Constipation: 1 person, 5.56%
- Dyspnea (difficult or laboured breathing): 1 person, 5.56%
- Fever: 1 person, 5.56%
- Mesenteric Vascular Insufficiency (insufficient vascular supply to mesenteric): 1 person, 5.56%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.56%
- Urinary Tract Infection: 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Rocephin and Thalomid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rocephin and Thalomid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rocephin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Thalomid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rocephin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Thalomid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ceftriaxone sodium and thalidomide (the active ingredients of Rocephin and Thalomid, respectively), and Rocephin and Thalomid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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