Rocephin and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Tracleer (bosentan). Common drug interactions include atrial fibrillation among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Rocephin and Tracleer. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.

On Jul, 17, 2026

41 people who take Rocephin and Tracleer together, and have interactions are studied.

Rocephin and Tracleer drug interactions.

What are the common drug interactions of Rocephin and Tracleer, by gender? *:

female:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Back pain
Cor pulmonale (enlargement of the right ventricle of the heart)
Heart rate increased
Heart rate irregular
Presyncope
Respiratory failure (inadequate gas exchange by the respiratory system)
Right ventricular failure (right half of the heart fails to work)
Sputum discoloured

male:

Dyspnoea (difficult or laboured respiration)
Cardiac failure
Respiratory distress (difficulty in breathing)
Viral infection
Abasia (inability to walk)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Alanine aminotransferase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)

What are the common drug interactions of Rocephin and Tracleer, by age (0-1 to 60+)? *:

0-1:

Pyrexia (fever)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Laryngomalacia (a congenital softening of the tissues of the larynx)
Otitis media (inflammation of the middle ear)
Respiratory failure (inadequate gas exchange by the respiratory system)
White blood cell count increased
Acute respiratory failure
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Corona virus infection (infection caused by a corona virus)
Dyspnoea (difficult or laboured respiration)

2-9:

n/a

10-19:

n/a

20-29:

Acute respiratory failure
Brain abscess
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cerebral haemorrhage (bleeding within the brain)
Coagulopathy (blood's ability to clot is impaired)
Gingival bleeding (bleeding gums)
Procedural complication
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Simple partial seizures (seizures which affect only a small region of the brain)

30-39:

Anxiety
Dyspnoea (difficult or laboured respiration)
Hypoxia (low oxygen in tissues)
Injection site reaction
Pruritus (severe itching of the skin)

40-49:

Dyspnoea (difficult or laboured respiration)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Arthralgia (joint pain)
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Pain in extremity
Pulmonary embolism (blockage of the main artery of the lung)
Acute respiratory failure
Anaemia (lack of blood)
Asthenia (weakness)

50-59:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Cardiac failure
Anaemia (lack of blood)
Blood creatinine increased
Dizziness
Drug level increased
Dyspnoea (difficult or laboured respiration)
Endocarditis (inflammation in heart muscle)
Fluid overload (too much fluid in the blood)
Flushing (the warm, red condition of human skin)

60+:

Dizziness
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Chest pain
Cough
Limb injury
Pulmonary hypertension (increase in blood pressure in the lung artery)
Ankle fracture
Arthralgia (joint pain)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 17 people, 41.46%
Anaemia (lack of blood): 5 people, 12.20%
Constipation: 4 people, 9.76%
Pneumonia: 4 people, 9.76%
Insomnia (sleeplessness): 3 people, 7.32%
Cancer Pain: 3 people, 7.32%
Cor Pulmonale Acute (rapid enlargement of the right ventricle of the heart): 3 people, 7.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 7.32%
High Blood Pressure: 3 people, 7.32%
Hypertrophic Cardiomyopathy (a condition in which the heart muscle becomes abnormally thick): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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