Rocephin and Zemuron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Zemuron (rocuronium bromide). Common drug interactions include hypertension among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Rocephin and Zemuron. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Zemuron?

Zemuron has active ingredients of rocuronium bromide. eHealthMe is studying from 873 Zemuron users. Check the latest studies of Zemuron.

On Jul, 31, 2026

21 people who take Rocephin and Zemuron together, and have interactions are studied.

What are the common drug interactions of Rocephin and Zemuron, by gender? *:

female:

Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Ischaemic nephropathy (damage to or disease of a kidney from insufficient blood supply)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Muscle haemorrhage (bleeding in muscle)
Peptic ulcer
Peripheral embolism (sudden interruption of blood flow to an organ or body part)

male:

Cardiac disorder
Abdominal pain
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fatigue (feeling of tiredness)
Haemorrhage subcutaneous (bleeding from skin)
Hypertension (high blood pressure)
Lip swelling
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the common drug interactions of Rocephin and Zemuron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hypertension (high blood pressure)

10-19:

Bone marrow failure
Bradycardia (abnormally slow heart action)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Cytokine storm (over-protective immune response that can actually be fatal)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematuria (presence of blood in urine)
Hyperkalaemia (damage to or disease of the kidney)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypotension (abnormally low blood pressure)

20-29:

n/a

30-39:

n/a

40-49:

Abdominal pain
Arthralgia (joint pain)
Back pain
Blood pressure decreased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Chest discomfort
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)

50-59:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Aspartate aminotransferase increased
Cardiac arrest
Thermal burn (burn by heat)
Transaminases increased
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematochezia (passage of stools containing blood)
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Decreased appetite
Blood pressure fluctuation
Bronchial hyperreactivity
Candidiasis (candidiasis or thrush is a fungal infection)
Cardiac disorder
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Clostridium difficile sepsis (infection(pus formation) of colon by clostridium difficile bacteria)
Death
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

Hypotension (abnormally low blood pressure): 5 people, 23.81%
Pneumonia: 4 people, 19.05%
Asthma: 3 people, 14.29%
Respiratory Tract Oedema (swelling of respiratory tract due to excess fluid collection in tissue): 3 people, 14.29%
Pain: 3 people, 14.29%
Multiple Myeloma (cancer of the plasma cells): 3 people, 14.29%
Constipation: 3 people, 14.29%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 14.29%
Headache (pain in head): 3 people, 14.29%
Type 2 Diabetes: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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