Roflumilast and Diovan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Roflumilast (roflumilast) and Diovan (valsartan). Common drug interactions include nausea among females and headache among males.
The phase IV clinical study analyzes what interactions people have when they take Roflumilast and Diovan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Roflumilast?
Roflumilast has active ingredients of roflumilast. eHealthMe is studying from 2,247 Roflumilast users. Check the latest studies of Roflumilast.
What is Diovan?
Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,154 Diovan users. Check the latest studies of Diovan.
18 people who take Roflumilast and Diovan together, and have interactions are studied.

What are the common drug interactions of Roflumilast and Diovan, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Asthenia (weakness)
- Headache (pain in head)
- Back pain
- Decreased appetite
- Diarrhoea
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Insomnia (sleeplessness)
- Swelling face
male:
- Headache (pain in head)
- Pneumonia
- Carbon monoxide diffusing capacity decreased
- Diastolic dysfunction
- Dyspnoea (difficult or laboured respiration)
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
- Fall
- Functional residual capacity decreased
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gouty arthritis (joint inflammation with crystal formation)
What are the common drug interactions of Roflumilast and Diovan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Headache (pain in head)
50-59:
- Abnormal sensation in eye
- Application site pain
60+:
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Back pain
- Decreased appetite
- Dizziness
- Influenza like illness
- Swelling face
- Aortic valve incompetence
- Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
- Carbon monoxide diffusing capacity decreased
What are the existing conditions these people have? *
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 50.00%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 22.22%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 5.56%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 5.56%
- Labyrinthitis (inflammation of the labyrinth or inner ear): 1 person, 5.56%
- High Blood Cholesterol: 1 person, 5.56%
- Gastritis (inflammation of stomach): 1 person, 5.56%
- Depression: 1 person, 5.56%
- Chronic Renal Failure (kidney failure): 1 person, 5.56%
- Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Roflumilast and Diovan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Roflumilast (2,247 reports)
- Diovan (83,154 reports)
Browse all drug interactions of Roflumilast and Diovan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Roflumilast:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Diovan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Roflumilast and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Diovan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on roflumilast and valsartan (the active ingredients of Roflumilast and Diovan, respectively), and Roflumilast and Diovan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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