Rowasa and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rowasa (mesalamine) and Doxycycline (doxycycline hyclate). Common drug interactions include depression among females and cardiac hypertrophy among males.

The phase IV clinical study analyzes what interactions people have when they take Rowasa and Doxycycline. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Rowasa?

Rowasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 943 Rowasa users. Check the latest studies of Rowasa.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,866 Doxycycline users. Check the latest studies of Doxycycline.

On Jul, 21, 2026

23 people who take Rowasa and Doxycycline together, and have interactions are studied.

Rowasa and Doxycycline drug interactions.

What are the common drug interactions of Rowasa and Doxycycline, by gender? *:

female:

Depression
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Inflammatory bowel disease
Malignant melanoma (skin cancer rises from melancytes)
Renal failure acute (rapid kidney dysfunction)
Uveitis (inflammation of the uvea)
Myalgia (muscle pain)
Headache (pain in head)
Muscular weakness (muscle weakness)
Pain in extremity

male:

Cardiac hypertrophy (thickening of the heart muscle)
Chest pain
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Pericarditis (inflammation of the pericardium)
Chronic kidney disease
Dehydration (dryness resulting from the removal of water)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

What are the common drug interactions of Rowasa and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Dehydration (dryness resulting from the removal of water)

10-19:

Chest pain
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Diarrhoea haemorrhagic (bloody diarrhoea)
Dysphagia (a condition in which swallowing is difficult or painful)
Insomnia (sleeplessness)
Myocarditis (inflammation of heart muscle myocardium)
Pericarditis (inflammation of the pericardium)
Pyelonephritis (inflammation of kidney caused by bacteria)
Pyrexia (fever)
Abdominal pain lower

20-29:

n/a

30-39:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Inflammatory bowel disease
Malignant melanoma (skin cancer rises from melancytes)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)
Uveitis (inflammation of the uvea)
Myalgia (muscle pain)
Headache (pain in head)

40-49:

Vasculitis necrotising (inflammation and damage to blood vessels)

50-59:

Blood creatinine increased
Blood urea increased
Inflammatory bowel disease
Malignant melanoma (skin cancer rises from melancytes)
Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Pain in extremity
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

n/a

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 21 people, 91.30%
Upper Respiratory Tract Infection: 11 people, 47.83%
Kidney Infection (Pyelonephritis): 11 people, 47.83%
Depression: 11 people, 47.83%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 47.83%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 5 people, 21.74%
Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal): 4 people, 17.39%
Hidradenitis (chronic disease of a type of sweat gland): 4 people, 17.39%

* Approximation only. Some reports may have incomplete information.

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