Roxanol and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxanol (morphine sulfate) and Doxycycline (doxycycline hyclate). Common drug interactions include compression fracture among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Roxanol and Doxycycline. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Roxanol?

Roxanol has active ingredients of morphine sulfate. eHealthMe is studying from 807 Roxanol users. Check the latest studies of Roxanol.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

19 people who take Roxanol and Doxycycline together, and have interactions are studied.

Roxanol and Doxycycline drug interactions.

What are the common drug interactions of Roxanol and Doxycycline, by gender? *:

female:

Compression fracture (fracture due to pressure caused by injury)
Deformity (disfigurement)
Dental caries
Depression
Discomfort
Dyspnoea (difficult or laboured respiration)
Emotional distress
Exostosis (formation of new bone on the surface of a bone)
Facial pain
Foot fracture

male:

Confusional state
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Aortic valve incompetence
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Blindness transient (sudden loss of vision)
Blood albumin decreased
Blood glucose increased
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the common drug interactions of Roxanol and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain upper
Acute respiratory distress syndrome
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anisocytosis (patient's red blood cells are of unequal size)
Anxiety
Asthenia (weakness)
Back pain
Beta 2 microglobulin increased
Blood calcium decreased
Blood glucose increased

40-49:

Blood triglycerides increased
Body temperature increased
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone pain
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Burning sensation
Cardiomyopathy (weakening of the heart muscle)
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)

50-59:

Chest discomfort
Death
Rash

60+:

Confusional state
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Aortic valve incompetence
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Blindness transient (sudden loss of vision)
Blood albumin decreased
Blood glucose increased
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Pain: 3 people, 15.79%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 10.53%
Stress And Anxiety: 2 people, 10.53%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 10.53%
Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 1 person, 5.26%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 5.26%
Breast Cancer: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Roxanol and Doxycycline?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously