Roxanol and Thalidomide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxanol (morphine sulfate) and Thalidomide (thalidomide). Common drug interactions include osteolysis among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Roxanol and Thalidomide. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Roxanol?

Roxanol has active ingredients of morphine sulfate. eHealthMe is studying from 807 Roxanol users. Check the latest studies of Roxanol.

What is Thalidomide?

Thalidomide has active ingredients of thalidomide. eHealthMe is studying from 16,473 Thalidomide users. Check the latest studies of Thalidomide.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

53 people who take Roxanol and Thalidomide together, and have interactions are studied.

Roxanol and Thalidomide drug interactions.

What are the common drug interactions of Roxanol and Thalidomide, by gender? *:

female:

Osteolysis (dissolution of bone)
Pain
Pain in jaw
Blood lactate dehydrogenase increased
Injury
Pain in extremity
Pneumonia
Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Back pain

male:

Anxiety
Pain
Decreased appetite
Constipation
Pleural effusion (water on the lungs)
Discomfort
Emotional distress
Fatigue (feeling of tiredness)
Spinal cord compression
Cardiomegaly (increased size of heart than normal)

What are the common drug interactions of Roxanol and Thalidomide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Asthma
Chest pain
Headache (pain in head)
Oedema lower limb (fluid collection in tissue of lower leg)
Pain in limb

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Pain
Pain in jaw
Spinal compression fracture (fracture due to spinal compression on bone)
Bone disorder
Loose tooth
Mastication disorder (disease of chewing food)
Cardiomegaly (increased size of heart than normal)
Decreased appetite

50-59:

Hypophagia (reduced food intake)
Intervertebral disc degeneration (spinal disc degeneration)
Osteonecrosis of jaw (death of bone of jaw)
Pleural fibrosis (formation of fibrous tissue in lung)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
Arthropathy
Haematochezia (passage of stools containing blood)
Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
Post laminectomy syndrome
Spondylitis (an inflammation of the vertebra with spinal cord involvement)

60+:

Anxiety
Blood lactate dehydrogenase increased
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Blood creatinine increased
Bone disorder
Bone fissure
Bruxism (habitual grinding of the teeth, typically during sleep)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 24 people, 45.28%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 13 people, 24.53%
Bone Density Decreased: 13 people, 24.53%
Pain: 11 people, 20.75%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 11 people, 20.75%

* Approximation only. Some reports may have incomplete information.

Do you take Roxanol and Thalidomide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously