Roxicet and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxicet (acetaminophen; oxycodone hydrochloride) and Compazine (prochlorperazine maleate). Common drug interactions include gastrointestinal haemorrhage among females and actinomycotic skin infection among males.

The phase IV clinical study analyzes what interactions people have when they take Roxicet and Compazine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Roxicet?

Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,254 Roxicet users. Check the latest studies of Roxicet.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 13, 2026

11 people who take Roxicet and Compazine together, and have interactions are studied.

Roxicet and Compazine drug interactions.

What are the common drug interactions of Roxicet and Compazine, by gender? *:

female:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Alopecia (absence of hair from areas of the body)
Alopecia areata (patchy baldness that typically begins with rapid hair loss)
Alopecia totalis (loss of all head hair)
Anaemia (lack of blood)
Catheter site erythema (redness of skin at catheter site)
Catheter site swelling
Chest pain
Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Decreased appetite

male:

Actinomycotic skin infection (infectious and inflammatory diseases affect the skin and the oral mucosa)
Acute sinusitis
Bone disorder
Bone pain
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast cancer metastatic
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cellulitis (infection under the skin)
Cervix inflammation
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Roxicet and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anxiety
Emotional distress
General physical health deterioration (weak health status)
Injury
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Death
Fatigue (feeling of tiredness)
Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
Metastases to kidney (cancer spreads to kidney)
Muscular weakness (muscle weakness)
Proteinuria (presence of protein in the urine)
Wheezing (a high-pitched whistling sound made while you breath)

50-59:

Anaemia (lack of blood)
Anxiety
Catheter site erythema (redness of skin at catheter site)
Catheter site swelling
Chest pain
Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Death
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Actinomycotic skin infection (infectious and inflammatory diseases affect the skin and the oral mucosa)
Back pain
Bone disorder
Bone pain
Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast cancer metastatic
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cellulitis (infection under the skin)
Cervix inflammation

What are the existing conditions these people have? *

Breast Cancer Female: 3 people, 27.27%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 18.18%
Ovarian Cancer (cancer of ovary): 1 person, 9.09%
Nausea (feeling of having an urge to vomit): 1 person, 9.09%
Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
Metastases To Liver (cancer spreads to liver): 1 person, 9.09%
Metastases To Kidney (cancer spreads to kidney): 1 person, 9.09%
Metastases To Bone (cancer spreads to bone): 1 person, 9.09%
Mesothelioma (rare type of cancer that occurs in the thin layer of cells lining the body's internal organs, known as the mesothelium): 1 person, 9.09%
Malignant Peritoneal Neoplasm (cancer tumour of peritoneum): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Roxicet and Compazine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously