Roxicodone and Acyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxicodone (oxycodone hydrochloride) and Acyclovir (acyclovir). Common drug interactions include intervertebral disc disorder among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Roxicodone and Acyclovir. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

On Aug, 04, 2026

67 people who take Roxicodone and Acyclovir together, and have interactions are studied.

Roxicodone and Acyclovir drug interactions.

What are the common drug interactions of Roxicodone and Acyclovir, by gender? *:

female:

Intervertebral disc disorder (spinal disc disorder)
Leukopenia (less number of white blood cells in blood)
Lumbar vertebral fracture
Myalgia (muscle pain)
Neurofibroma (non-cancerous tumours that grow on nerves throughout the body)
Neuropathy peripheral (surface nerve damage)
Osteomyelitis (infection of bone)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))

male:

Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bone disorder
Breast mass
Calculus ureteric (stone in ureter)
Cellulitis (infection under the skin)
Costochondritis (chest wall pain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dental caries

What are the common drug interactions of Roxicodone and Acyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Haemorrhage intracranial (bleeding within the skull)

40-49:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Cardiac arrest
Encephalopathy (functioning of the brain is affected by some agent or condition)
Bacteraemia (presence of bacteria in the blood)
Chronic kidney disease
Drug ineffective
Nephrogenic anaemia (anaemia due to kidney disease)
Nervousness
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bone density decreased
Bone loss
Cardiac failure congestive
Chills (felling of cold)
Depression
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)

60+:

Thrombocytopenia (decrease of platelets in blood)
Anaemia (lack of blood)
Leukopenia (less number of white blood cells in blood)
Neuropathy peripheral (surface nerve damage)
Osteonecrosis of jaw (death of bone of jaw)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Arthralgia (joint pain)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysphonia (speech disorder attributable to a disorder of phonation)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 19 people, 28.36%
Muscle Spasms (muscle contraction): 13 people, 19.40%
Nausea (feeling of having an urge to vomit): 12 people, 17.91%
High Blood Pressure: 9 people, 13.43%
Constipation: 8 people, 11.94%
Type 2 Diabetes: 5 people, 7.46%
Neuropathy Peripheral (surface nerve damage): 4 people, 5.97%
Insomnia (sleeplessness): 4 people, 5.97%
Infection: 4 people, 5.97%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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