Roxicodone and Hydrodiuril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxicodone (oxycodone hydrochloride) and Hydrodiuril (hydrochlorothiazide). Common drug interactions include vitamin d deficiency among females and cholecystitis acute among males.

The phase IV clinical study analyzes what interactions people have when they take Roxicodone and Hydrodiuril. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

What is Hydrodiuril?

Hydrodiuril has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 4,211 Hydrodiuril users. Check the latest studies of Hydrodiuril.

On Jul, 12, 2026

59 people who take Roxicodone and Hydrodiuril together, and have interactions are studied.

Roxicodone and Hydrodiuril drug interactions.

What are the common drug interactions of Roxicodone and Hydrodiuril, by gender? *:

female:

Vitamin d deficiency
White blood cell count increased
Anaemia (lack of blood)
Lymphocyte count decreased
Abdominal pain lower
Asthenia (weakness)
Decreased appetite
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

male:

Cholecystitis acute (rapid infection of gallbladder)
Fatigue (feeling of tiredness)
Periorbital oedema (swelling around the eyes)
Platelet count decreased
Renal failure (kidney dysfunction)
Vomiting
Alopecia (absence of hair from areas of the body)
Aspartate aminotransferase increased
Blood bilirubin increased
Constipation

What are the common drug interactions of Roxicodone and Hydrodiuril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Papillary thyroid cancer
Decreased appetite
Dizziness
Erection increased
Fatigue (feeling of tiredness)
Follicular thyroid cancer (cancer of the thyroid)
Hypotension (abnormally low blood pressure)

50-59:

Obesity (having too much body fat)
Oedema peripheral (superficial swelling)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sensation of foreign body
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Swelling
Type i hypersensitivity
Vitamin d deficiency
Blood glucose increased
Haemoglobin decreased

60+:

Fatigue (feeling of tiredness)
Constipation
Anaemia (lack of blood)
Asthenia (weakness)
Cholecystitis acute (rapid infection of gallbladder)
Chronic kidney disease
Pain in extremity
Renal failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
White blood cell count decreased

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 10 people, 16.95%
Stress And Anxiety: 7 people, 11.86%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 10.17%
Thermal Burn (burn by heat): 6 people, 10.17%
Itching: 6 people, 10.17%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.47%
Constipation: 5 people, 8.47%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 8.47%
Hypokalemia (low potassium): 5 people, 8.47%
Back Pain: 4 people, 6.78%

* Approximation only. Some reports may have incomplete information.

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