Roxicodone and Vyvanse drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxicodone (oxycodone hydrochloride) and Vyvanse (lisdexamfetamine dimesylate). Common drug interactions include blindness among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Roxicodone and Vyvanse. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

What is Vyvanse?

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,870 Vyvanse users. Check the latest studies of Vyvanse.

On Aug, 04, 2026

12 people who take Roxicodone and Vyvanse together, and have interactions are studied.

Roxicodone and Vyvanse drug interactions.

What are the common drug interactions of Roxicodone and Vyvanse, by gender? *:

female:

Blindness
Vision blurred
Chest discomfort
Drug screen positive
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Sensation of heaviness

male:

Anxiety
Oligodendroglioma (a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Nausea (feeling of having an urge to vomit)
Peripheral swelling
Drug abuse
Drug dependence
Loss of consciousness
Road traffic accident

What are the common drug interactions of Roxicodone and Vyvanse, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Peripheral swelling

20-29:

n/a

30-39:

Drug screen positive
Anxiety
Oligodendroglioma (a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blindness
Nausea (feeling of having an urge to vomit)
Vision blurred

40-49:

n/a

50-59:

Chest discomfort
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Sensation of heaviness

60+:

n/a

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 25.00%
Rickets (softening of bones): 3 people, 25.00%
Nausea And Vomiting: 3 people, 25.00%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 25.00%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 25.00%
Headache (pain in head): 1 person, 8.33%
Cough: 1 person, 8.33%
Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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