Ruxience and Bendamustine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ruxience (rituximab-pvvr) and Bendamustine (bendamustine). Common drug interactions include clostridium difficile colitis among females and disease progression among males.

The phase IV clinical study analyzes what interactions people have when they take Ruxience and Bendamustine. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Ruxience?

Ruxience has active ingredients of rituximab-pvvr. eHealthMe is studying from 4,260 Ruxience users. Check the latest studies of Ruxience.

What is Bendamustine?

Bendamustine has active ingredients of bendamustine. eHealthMe is studying from 9,508 Bendamustine users. Check the latest studies of Bendamustine.



On Jul, 15, 2026

23 people who take Ruxience and Bendamustine together, and have interactions are studied.

Ruxience and Bendamustine drug interactions.

What are the common drug interactions of Ruxience and Bendamustine, by gender? *:

female:

  1. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  2. Disease progression
  3. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  4. Drug ineffective
  5. Death
  6. Pneumonia
  7. Neoplasm progression (growth of tumour)
  8. Deafness
  9. Oedema (fluid collection in tissue)
  10. Pyrexia (fever)

male:

  1. Disease progression
  2. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  3. Platelet count decreased
  4. Renal failure (kidney dysfunction)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Mantle cell lymphoma (cancer of lymphocytes, a type of white blood cell)
  7. Neoplasm progression (growth of tumour)
  8. Anaemia (lack of blood)
  9. Cardiomyopathy (weakening of the heart muscle)
  10. Deafness

What are the common drug interactions of Ruxience and Bendamustine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  2. Disease progression
  3. Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
  4. Drug ineffective
  5. Pneumonia
  6. Neoplasm progression (growth of tumour)

60+:

  1. Disease progression
  2. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  3. Platelet count decreased
  4. Renal failure (kidney dysfunction)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Mantle cell lymphoma (cancer of lymphocytes, a type of white blood cell)
  7. Death
  8. Neoplasm progression (growth of tumour)
  9. Anaemia (lack of blood)
  10. Cardiomyopathy (weakening of the heart muscle)

What are the existing conditions these people have? *

  1. Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 9 people, 39.13%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 30.43%
  3. Richter's Syndrome (hairy cell cancer changes in fast growing b cell cancer tumour): 5 people, 21.74%

* Approximation only. Some reports may have incomplete information.

Do you take Ruxience and Bendamustine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ruxience and Bendamustine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ruxience:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bendamustine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ruxience and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bendamustine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rituximab-pvvr and bendamustine (the active ingredients of Ruxience and Bendamustine, respectively), and Ruxience and Bendamustine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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