Rythmol and Imodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Imodium (loperamide hydrochloride). Common drug interactions include cough among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Imodium. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

On Aug, 04, 2026

14 people who take Rythmol and Imodium together, and have interactions are studied.

What are the common drug interactions of Rythmol and Imodium, by gender? *:

female:

Cough
Dehydration (dryness resulting from the removal of water)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Fall
Glaucoma (increased fluid pressure in the eye with vision loss)
Hepatic steatosis (fatty liver disease)
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)

male:

Hypotension (abnormally low blood pressure)
Renal failure (kidney dysfunction)
Pain
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abdominal pain
Atrioventricular block (heart block)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cardiac failure congestive
Chest pain

What are the common drug interactions of Rythmol and Imodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaemia macrocytic (a macrocytic class of anaemia)
Anxiety
Aortic dilatation
Arteriovenous fistula
Arthralgia (joint pain)
Back disorder
Back pain
Blood albumin decreased
Blood bicarbonate decreased
Blood creatinine increased

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Renal failure (kidney dysfunction)
Anxiety
Dyspnoea (difficult or laboured respiration)
Fall
Proteinuria (presence of protein in the urine)
Thrombocytopenia (decrease of platelets in blood)
Anaemia macrocytic (a macrocytic class of anaemia)
Arteriovenous fistula
Back pain
Carotid artery stenosis (narrowing of carotid artery)

What are the existing conditions these people have? *

Pain: 9 people, 64.29%
Multiple Myeloma (cancer of the plasma cells): 6 people, 42.86%
Limb Discomfort (discomfort in leg): 6 people, 42.86%
Acute Kidney Failure: 6 people, 42.86%
Oesophageal Carcinoma (cancer tumour of oesophagus): 3 people, 21.43%
Nausea (feeling of having an urge to vomit): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

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