Rythmol and Klonopin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Klonopin (clonazepam). Common drug interactions include hand fracture among females and haemoglobin decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Klonopin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

On Aug, 09, 2026

36 people who take Rythmol and Klonopin together, and have interactions are studied.

What are the common drug interactions of Rythmol and Klonopin, by gender? *:

female:

Hand fracture
Intervertebral disc disorder (spinal disc disorder)
Lip injury
Liver disorder (liver diseases)
Lung disorder (lung disease)
Oesophageal dilatation (enlarged oesophagus)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Polyp
Renal failure (kidney dysfunction)
Tendon disorder (disease of tendon)

male:

Haemoglobin decreased
Diarrhoea
Pneumonia
Pruritus (severe itching of the skin)
Pyrexia (fever)
Vertigo
White blood cell count decreased
Anaemia (lack of blood)
Blood pressure decreased
Cardiac disorder

What are the common drug interactions of Rythmol and Klonopin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dyspnoea (difficult or laboured respiration)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Chest pain

50-59:

Cardiovascular disorder (heart diseases)
Emotional distress
Injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Neuropathy peripheral (surface nerve damage)
Pain
Skin injury

60+:

Dyspnoea (difficult or laboured respiration)
Dysphagia (a condition in which swallowing is difficult or painful)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Syncope (loss of consciousness with an inability to maintain postural tone)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Weight decreased
Alopecia (absence of hair from areas of the body)
Anaphylactic reaction (serious allergic reaction)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 19.44%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 19.44%
Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 13.89%
Asthma: 5 people, 13.89%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 13.89%
Depression: 5 people, 13.89%
Pain: 5 people, 13.89%
Insomnia (sleeplessness): 4 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.11%
Gait Disturbance: 4 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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