Rythmol and Solu-medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Solu-medrol (methylprednisolone sodium succinate). Common drug interactions include amnesia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Solu-medrol. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

On Aug, 09, 2026

13 people who take Rythmol and Solu-medrol together, and have interactions are studied.

Rythmol and Solu-medrol drug interactions.

What are the common drug interactions of Rythmol and Solu-Medrol, by gender? *:

female:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Belligerence (aggressive or warlike behaviour)
Blood creatinine increased
Blood sodium decreased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dementia (madness)
Depressed level of consciousness
Drug dependence
Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)

male:

Anaemia (lack of blood)
Hypertension (high blood pressure)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Muscle spasms (muscle contraction)
Rash erythematous (redness of the skin)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Rythmol and Solu-Medrol, by age (0-1 to 60+)? *:

0-1:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug dependence
Pulmonary alveolar haemorrhage (acute bleeding)
Renal failure acute (rapid kidney dysfunction)
Acute respiratory failure

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Agitation (state of anxiety or nervous excitement)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Belligerence (aggressive or warlike behaviour)
Confusional state
Dementia (madness)
Depressed level of consciousness
Hostility
Psychotic disorder
Respiratory depression (respiration has a rate below 12 breaths)

60+:

Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)
Contusion (a type of hematoma of tissue in which capillaries)
Decreased appetite
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
Lung infection pseudomonal (bacterial infection of lung by pseudomonas aeruginosa)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 2 people, 15.38%
Colitis (inflammation of colon): 2 people, 15.38%
Breast Cancer: 2 people, 15.38%
Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 1 person, 7.69%
Sick Sinus Syndrome (a collection of heart rhythm disorders): 1 person, 7.69%
Sedation: 1 person, 7.69%
Hypolipidaemia (an abnormally high concentration of fats or lipids in the blood): 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 7.69%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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