Sabril and Robinul drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sabril (vigabatrin) and Robinul (glycopyrrolate). Common drug interactions include hypersomnia among females and atelectasis among males.

The phase IV clinical study analyzes what interactions people have when they take Sabril and Robinul. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Sabril?

Sabril has active ingredients of vigabatrin. eHealthMe is studying from 12,445 Sabril users. Check the latest studies of Sabril.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.

On Aug, 11, 2026

43 people who take Sabril and Robinul together, and have interactions are studied.

What are the common drug interactions of Sabril and Robinul, by gender? *:

female:

Hypersomnia (excessive daytime sleepiness (eds))
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Death
Optic atrophy (the loss of a proportion of optic disc nerve fibres)
Pneumonia
Abdominal discomfort
Diarrhoea
Nausea (feeling of having an urge to vomit)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)

male:

Atelectasis (partial or complete collapse of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Neonatal disorder (disease of neonates)
Pyrexia (fever)
Somnolence (a state of near-sleep, a strong desire for sleep)
Viral infection
Infantile spasms
Abnormal behaviour
Adverse event

What are the common drug interactions of Sabril and Robinul, by age (0-1 to 60+)? *:

0-1:

Neonatal disorder (disease of neonates)
Upper respiratory tract infection
Viral infection
Death
Nasopharyngitis (inflammation of the nasopharynx)
Pneumonia viral
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Dysphagia (a condition in which swallowing is difficult or painful)
Hospitalisation
Lung infection

2-9:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Respiratory distress (difficulty in breathing)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Pneumonia
Somnolence (a state of near-sleep, a strong desire for sleep)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Adverse event
Bacterial tracheitis (bacterial infection of the trachea)
Bradycardia (abnormally slow heart action)

10-19:

Hypersomnia (excessive daytime sleepiness (eds))
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abdominal discomfort
Diarrhoea
Nausea (feeling of having an urge to vomit)
Abnormal behaviour
Aggression
Somnolence (a state of near-sleep, a strong desire for sleep)
Adverse drug reaction
Cardiac arrest

20-29:

Apnoea (suspension of external breathing)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Seizure cluster (small group of seizure)
Urinary tract infection

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Infantile Spasms: 20 people, 46.51%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 14 people, 32.56%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 11 people, 25.58%
Wheezing (a high-pitched whistling sound made while you breath): 6 people, 13.95%
Pain: 5 people, 11.63%
Dyspnea (difficult or laboured breathing): 5 people, 11.63%
Constipation: 5 people, 11.63%
Hypersensitivity: 4 people, 9.30%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 9.30%
Seizure Cluster (small group of seizure): 3 people, 6.98%

* Approximation only. Some reports may have incomplete information.

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